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{
    "metadata": {
        "accession": "A0A5F9CKG7",
        "id": "A0A5F9CKG7_RABIT",
        "source_organism": {
            "taxId": "9986",
            "scientificName": "Oryctolagus cuniculus",
            "fullName": "Oryctolagus cuniculus (Rabbit)"
        },
        "name": "Casein kinase I isoform alpha",
        "description": [
            "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. Acts as a positive regulator of mTORC1 and mTORC2 signaling in response to nutrients by mediating phosphorylation of DEPTOR inhibitor. Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3"
        ],
        "length": 524,
        "sequence": "MASSSDSRAKLIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESLKAKHSQLLYESKVYKILQGGVGIPHIRWYGPEKDHNALVLDLLGPSLQDLFSFCSRKFTMKTVLMLADQMISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYRENKSFTGTARYASINAHLGIEQSRRDDMEALGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEILCKGFPAEFSMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKVSSGDSEAKPLIFTFVPTVRRLPTHTQLADTSKYLVKIPEEPSDKSPETVNRSNSNDYSILNTGSEQEKDQKILIDTSEVSENISQERRLKAKESQGMQQSDLFKAEYVFIVDSEGEDEATSKKDEQGPMGGTGSTAARPKTLAISSSLASDVVRPKKWGTDLKASSHPEMSHGLGPQQRHGQNPTTLPRAAGRETKYVSTFVIIHITYFMSAYVNYIVI",
        "proteome": "UP000001811",
        "gene": "MLIP",
        "go_terms": [
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "ida_accession": "03ab341ae4574f99080ed6ac9e349b8fc7c594db",
        "counters": {
            "domain_architectures": 1,
            "entries": 16,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 1,
                "pfam": 2,
                "profile": 1,
                "smart": 1,
                "panther": 1,
                "prosite": 2,
                "interpro": 6
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1
        }
    }
}