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{
    "metadata": {
        "accession": "A0A4W6GCN3",
        "id": "A0A4W6GCN3_LATCA",
        "source_organism": {
            "taxId": "8187",
            "scientificName": "Lates calcarifer",
            "fullName": "Lates calcarifer (Barramundi)"
        },
        "name": "Riboflavin kinase",
        "description": [
            "Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase"
        ],
        "length": 199,
        "sequence": "MKSLPFFCRGEVIRGFGRGSKELGIPTANFPDTVVDSLPADISTGIYYGWACVGNGDVHKMVMSIGWNPYYKNTKKSMETHVIHKFKEDFYGEILSVVMVGYIRPERSYNSLGMTPPHTHTHIIFVCLVSKTSFSALPDFISQFFLFTYHVYSVPIISFFPSVLNSVTYTHSLTLLTCLSACFYLFLNRGSNCSHQQRH",
        "proteome": "UP000314980",
        "gene": "RFK",
        "go_terms": [
            {
                "identifier": "GO:0008531",
                "name": "riboflavin kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0009398",
                "name": "FMN biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0009231",
                "name": "riboflavin biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "8abc233ca252e50cc4068a9aadf249acd1450c55",
        "counters": {
            "domain_architectures": 4957,
            "entries": 10,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 1,
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 4957
        }
    }
}