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{
"metadata": {
"accession": "A0A010RX37",
"id": "A0A010RX37_9PEZI",
"source_organism": {
"taxId": "1445577",
"scientificName": "Colletotrichum fioriniae PJ7",
"fullName": "Colletotrichum fioriniae PJ7"
},
"name": "E3 ubiquitin-protein ligase listerin",
"description": [
"E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription",
"E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation"
],
"length": 1635,
"sequence": "MSRAFGKSSRSSGAARGFGSPAPAGFGGFSSAGGSGLSYLSEPPNLTSISDANVVVAFKNALKKDATTKAKALEDLLAYVQAHPFEVEGGVEESILEAWVQIYPRISIDNSRRVRELSHTLQFELMKSARKRMEKRVPKIVGTWLAGLYDKDRVVSRAANDGLSSFLSSPEKVAMFWSKCQSQILTYATDAIQETKDTLSDERSTTADDAEAKYLRVIGASLSLVLGLLQKLDATDIQREEEAYDTFFAEEKVWKSVVTGDSSVKKTACQLLWACLDKRFDSVSSQISRLKKTFVAEGLKSSQVGSAVEYVRVLTKLTAKFPEIWTSSSEKKTPITRLNGFLEKGSQSSSVKYWEHLEYLIKAIPTELFTVDASADALKSMRTGITSREEPRMNATAAWTCYARTTKHLLKTFSSDSERATLVQEHLFPLIEHFLLPTPENSSWEIAGNGRLPVLGEVYEVSVGSSSEELKATSDKLGLLSSAFCGRISNSLPEVSKDYEKSQEAIASEGTRWFTLVGQVQKANPKDSLFVEPSRVIIKCSVDLLATRNLKPYGAAAVLYSVSKNAPHVWRDAEAAQALEQFLSTQGRDRMDVLMLSRSGTDLLNCANALGTLDGQEAIYANIWNTWIEALLSLSDDSQAIRGIERLIANQKASDLSQSHEQLQKFIESKCSSTARGDLDAWSLFEAAFSNNAIADSTAKQLVDNSVSALSQNKQHSVQALRSLEIIANNKPGLLSQDESTHMAVVTELLGLAELNDRAISPRAASLRALLEQPADGVSPVVTIIQRNLEDAGPQSLGVDTLVQQALQASSQAGSIAIEDLFPSTNIWMQQLSKFFQAKLNPSLSITSGLAGAHFLVQPTESDQRLRVRRDRDGLSIPARMASYTSKLLSSDISVSSLPDSFQVELLYLLCVAVQMVSDQITLMDEHKLFLNLDMGDALASAESFVSSTRLTINAIVDEAKGWRDGSEAGSTKLVNGLIAIMTQETKELTPLGVYSSRALSDLFQNLAEKHGFPVAGDEKINQLATLKATPPTILAATAVLAGFGESLESSKSINNLCNRLVSDIAGASVEPEKAEKTLLILVLLNACLQVYEVGGVPVANNRIVFAVRQITSWMDDIPNLTPALSAEICRSLQRLLPCMKDVYGSYWDKTIEFSTALWARASDDRLDDSLPYIHASLKLMTALETLSEPNDDLVDAIKEFAETKSLSLIELLKLDREKNTQPLEIVDAIICRQVNKIPLKHVTDLSDLYGLIAADSRSIQTAAFNLLHYALPARQEELSVNVLLDKTDARLPDELLSLLLDAPTLDRYPDEILAQFPLAIRSYLLSWHLIFDAFSTASLKVRQDYTEHLKTENYIAPLMDFTFDVLGHSAAHPLNLEREGLTTQHLISYSVSLADAEPDERNLHWLLVHLYYLTLKYTPGLFKTWYLDCRSKQTRIAVEGWMTRYFSPIIVSDALDEVAAWAAAQDPPADDDEKELVVKVSKASREITAGVEIDESMASIAVKVPASYPIEGVSVVGINRVAVNERKWQSWLLTTQGVITFSNGSIIDGLSAFRRNIVGALKGQSECAICYSIISSDKRMPDKRCSTCKNLFHRTCLYKWFQSSNQNTCPLCRNPIDYLGHDSRAKRGQSDYVV",
"proteome": "UP000020467",
"gene": "CFIO01_09000",
"go_terms": [
{
"identifier": "GO:0061630",
"name": "ubiquitin protein ligase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:1990116",
"name": "ribosome-associated ubiquitin-dependent protein catabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:1990112",
"name": "RQC complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": false,
"in_bfvd": false,
"ida_accession": "3eb8557e293425c1be77e71fae6e578e0d37f900",
"counters": {
"domain_architectures": 571,
"entries": 22,
"isoforms": 0,
"proteomes": 1,
"sets": 4,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 5,
"ssf": 2,
"cathgene3d": 1,
"smart": 2,
"cdd": 1,
"profile": 1,
"panther": 1,
"interpro": 9
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 571
}
}
}
