HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "W9KGL6",
"id": "W9KGL6_FUSOX",
"source_organism": {
"taxId": "660027",
"scientificName": "Fusarium oxysporum Fo47",
"fullName": "Fusarium oxysporum Fo47"
},
"name": "RNA polymerase II transcription factor B subunit 2",
"description": [
"Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA",
"Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription"
],
"length": 496,
"sequence": "MSVSPAPSLQLAEYLEKLPGTTFRKLYQQPSTAFAIFRRMLPHLAKTFVMRILYSPKPILLSDLDDWVKPSHKRQKDQALSILRVLHIVSITAPSKERPQEMQLTTNFKLSLRLALSGGGTHNSFGVPSTLQIPPEIDIAFLDRYARKKWEDILHFVVSSVGYKSAGESSGPNKSVKELLVAGRLVDRKASGSVGITQAGFTFLLQEANAQVWTLLLLWLEAMEVNKMAGLEATDMLSFLFVLASMELGRAYDTNALTEQRKNMLPSLVDFGLIYIPNHKRSMFFPTRLATTLTSSSNSLRSISDGVAAATAAALQPGQSGAPGGSVTAANTEQRGSVIIETNYRIYAYTQSTLQIAVLALFTKLAMRFPDMVAGRISRQSIRQAIQFGITAEQIISYLSAHAHDQMHRTAALNNKPVLPPTVVDQIRLWQLENERMKTTSGFLFKSFEDDREYKDIARFAEEVGVLVWKNDARQMFFASKHEQIRDYMKIRKKTE",
"proteome": null,
"gene": "FOZG_09147",
"go_terms": [
{
"identifier": "GO:0001671",
"name": "ATPase activator activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006289",
"name": "nucleotide-excision repair",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0000439",
"name": "transcription factor TFIIH core complex",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "08b95e0fc3d8c2323c16fcc9d416c942feea0baa",
"counters": {
"domain_architectures": 3576,
"entries": 7,
"isoforms": 0,
"proteomes": 0,
"sets": 0,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"pfam": 2,
"panther": 1,
"ncbifam": 1,
"interpro": 2
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 3576
}
}
}