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{
"metadata": {
"accession": "W7RF79",
"id": "W7RF79_LYSSH",
"source_organism": {
"taxId": "1400869",
"scientificName": "Lysinibacillus sphaericus CBAM5",
"fullName": "Lysinibacillus sphaericus CBAM5"
},
"name": "D-alanine--D-alanyl carrier protein ligase",
"description": [
"Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall"
],
"length": 491,
"sequence": "MLSILAAIERVAIQQPQKTAYQTHNASLTYGELWHFSDCIADYIMTHHLQRQQPIVVYGHMSPLQIVAFLGAVKAGHPYVPVDSSTPSERLQLILEASKAGLLFTTEPLQMLTNIPVVAVSDVLDSPSLPNSPATRDWVQQEDIHYIIYTSGSTGQPKGVQITANNLAHFVTWMQEHFPLQKSGVFLNQAPYSFDLSVMDLYPALVGGHTLYAITQQEIANPRALFDSLALSNTRVWTSTPSFAKMCLMNKEWEQQLMPALDTFLFCGEVLPIAVIKELMQRFPQATIYNLYGPTETTVAVSYVKVTKALLEQFEQLPIAPISEPNVSLLDDGEIVISGSTVSAGYLGAPELTAKAFPTVDGHRIYQTGDMGYEQDGYLFFLGRKDFQVKLHGYRLEIEEIEKQISNLPPVSSCVVVPVYKDKEIVSLNAHIVLREPLADSAFKMTKQLKALLSEYLPAYMIPRTFKYMDALPLNANGKVDRKGLAVMETV",
"proteome": null,
"gene": "dltA",
"go_terms": [
{
"identifier": "GO:0005524",
"name": "ATP binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0047473",
"name": "D-alanine [D-alanyl carrier protein] ligase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0070395",
"name": "lipoteichoic acid biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "ba6ba0b0e99fc7c9ffcc323888fecbac8c6c4763",
"counters": {
"domain_architectures": 241937,
"entries": 20,
"isoforms": 0,
"proteomes": 0,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"ssf": 1,
"cdd": 1,
"pfam": 2,
"hamap": 1,
"ncbifam": 3,
"panther": 1,
"prosite": 1,
"interpro": 8
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 241937
}
}
}