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InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "W5URL0",
"id": "W5URL0_ICTPU",
"source_organism": {
"taxId": "7998",
"scientificName": "Ictalurus punctatus",
"fullName": "Ictalurus punctatus (Channel catfish)"
},
"name": "8-oxo-dGDP phosphatase NUDT18",
"description": [
"Mediates the hydrolysis of oxidized nucleoside diphosphate derivatives. Hydrolyzes 8-oxo-7,8-dihydroguanine (8-oxo-Gua)-containing deoxyribo- and ribonucleoside diphosphates to the monophosphates. Hydrolyzes 8-oxo-dGDP and 8-oxo-GDP with the same efficiencies. Also hydrolyzes 8-OH-dADP and 2-OH-dADP. Exhibited no or minimal hydrolysis activity against 8-oxo-dGTP, 8-oxo-GTP, dGTP, GTP, dGDP and GDP. Probably removes oxidized guanine nucleotides from both the DNA and RNA precursor pools"
],
"length": 328,
"sequence": "MDSVDEDVEEKVEKMLNGEGLEVLDIDAVPDHVQAVTLKKNICYIVSAVIFNSEGQVLMVQEAKRECYGLWYLPAGRMEAGESIHEALRREVKEETGFECEPITMLLVQEQGRQWIRFAFLAKVTGGRLKTPSEADLESLQARWWDREAPLPLRSQDILCLIDAGLRYRQKPWFPVSHPVNLPCSVVCQRQLLIFGCEERIWLLLAKHATDPETRTRFPVTVSQKGYSVKCAGQRLVRECMRSRDHELHVNVHGILGVQHDGRVLGRSDGICFNTLATLERSGEGAELSSLPLLDSKGYTWHEVTDQSLKGKILRRIKDRSFLPMHSL",
"proteome": "UP000221080",
"gene": "nudt18",
"go_terms": [
{
"identifier": "GO:0017110",
"name": "nucleoside diphosphate phosphatase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016787",
"name": "hydrolase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 2,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "752b3b6d9807717ea1f029db1420a2538cb188ca",
"counters": {
"domain_architectures": 250306,
"entries": 13,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"profile": 1,
"cdd": 1,
"pfam": 1,
"panther": 1,
"prints": 1,
"prosite": 1,
"interpro": 5
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 250306
}
}
}