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{
    "metadata": {
        "accession": "U3J141",
        "id": "U3J141_ANAPP",
        "source_organism": {
            "taxId": "8840",
            "scientificName": "Anas platyrhynchos platyrhynchos",
            "fullName": "Anas platyrhynchos platyrhynchos (Northern mallard)"
        },
        "name": "E3 ubiquitin-protein ligase",
        "description": [
            "Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation"
        ],
        "length": 1751,
        "sequence": "MAAELEAEVPAFDRGLLECSAEEIAAKWLQGSELQKEVYRHLAYYVPKIYCRGPNPAPQREDMLAQHVLLGPMEWYLCGEDPAFGFPKLEQANKPSHLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHREHRYRMTTSSGGGFCDCGDTEAWKEGPYCQKHELNTSETAEEEDPLVHLPEDMVARAYNIFAITFKYAVDILTWEKENELPGLEMIEKNDTYYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCDQAKSVIVRNTSRQTKPLKVQVMHSSIVAHQSFGLKLLTWLGSVIGYSDGLRRILCQVGLQEGPDGENSSLVDKLMLYDSKLWKGARNVYHQLFMSSLLMDLKCKKLFAIRFARNYRQLQRDYMEDDHDRAVSVAALSVQLFTVPTLARMLITEENLMTTIIKTFMDHLRHRDIQGRFQFERYTALQAFKFRRVQSLILDLKYVLISKPTEWSEDLRHKFLEGFDAFLELLKCMQGMDPITRQVGQHIEMEPEWEAAFTLQMKLTLVISMMQDWCALDEKVLIEAYKKCLTVLMQCHSGFTDGEQPIVLSMCGHSVETIRYCVSQEKVSIHLPVSRLLAGLHVLLSKTEVAYKFPELLPLSELSPPMLIEHPLRCLVLCAQVHAGMWRRNGFSLVNQIYYYHNVKCRREMFDKDIVMLQTGVSMMDPNHFLMIMLSRFELYQIFSTPDYGKRFSTENTNKDVVQQNNTLIEEMLYLIIMIVGERFSPGIGQVNATDEIKREIIHQLSIRPMAHSELVKALPEDENRETGMESVIEEVACFKKPGLTGRGLYELKPECTKNFNLYFYHFSRAEQSKAEEAQRKLKRQNREDTALPPPALPPFCPLFASLINVLQSDVMLCIMGTILQWAVEHNGYAWSESMLQRVLHLIGMALQEEKQHLENLSEENVVTFTFTQKISRPGEAPNNSPSILAMLETLQNAPHLEVHKDMIRWILKTFNTIKKLRESSSTSPVAETEGNVMEESSRDKDKAERKRKAEIARLRREKIMAQMSEMQRHFINENKELFQQTLEELDTSASGGHDNSPVISDAKLTALGPEQTRVAEHRQVVMCILCQEEQEVKVDSRAMVLAAFIQRSTVLSKNRNRIIPDPEKYDPLFMHPDLSCGTHTGSCGHIMHAHCWQRYFDAVQAKEQRRQQRLRVHTSYDVENGEFLCPLCECLSNTVIPLLPPPRVLFNRLDFSGQPNLSQWIKTISQQMKALYLLRDEDHSSNSSSSEKMDQLQLPEGFRPDYKPKNPYSESIKEMLTTFGTATYKVGLKVHPNEEDPRVPIMCWGSCAYTIQTIERILADEDKPLFGHLPCRQDDCLKSLTRFAAAHWTVSSLSAVQGHFCTLLASLVPNEKNGNLPCILDIDMFHLLVSLVLSFPAIHCQDFSGVSLGTGDLHLFHLVTMAHIIQILLTSSTEENGMDQEDTSGEEEVAVLTLYKFLCQCTGSALKEVSSGWHLWRNLKAGIMPFLRCSALFFHYLNGVPAPSELQVNGTSQFEHLCSYLSLPNNLTCLFQENSEILNTLVESWCSSNEVKRYLEGKRHAISYARESNKLIDLPDDYSCLINQASNFSCPKSGGDKSRAPTLCLVCGTMLCSQSYCCQTELEGEDVGACTAHTYTCGSGVGIFLRVRECQVLFLAGKTKGCFYPPPYLDDYGETDQGLRRGNPLHLCKERFKKIQKLWQQHSITEEIGHAQEANQTLVGIDWQHL",
        "proteome": "UP000016666",
        "gene": "UBR2",
        "go_terms": [
            {
                "identifier": "GO:0008270",
                "name": "zinc ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0061630",
                "name": "ubiquitin protein ligase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0071596",
                "name": "ubiquitin-dependent protein catabolic process via the N-end rule pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0030163",
                "name": "protein catabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "5696b282a9e71c88df01beac41c868c8241dad06",
        "counters": {
            "domain_architectures": 3585,
            "entries": 23,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "smart": 1,
                "profile": 1,
                "cdd": 2,
                "cathgene3d": 3,
                "ssf": 2,
                "pfam": 4,
                "panther": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3585
        }
    }
}