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{
    "metadata": {
        "accession": "Q9XXH8",
        "id": "CNT1_CAEEL",
        "source_organism": {
            "taxId": "6239",
            "scientificName": "Caenorhabditis elegans",
            "fullName": "Caenorhabditis elegans"
        },
        "name": "Arf-GAP with ANK repeat and PH domain-containing protein cnt-1",
        "description": [
            "GTPase-activating protein for the ADP ribosylation factor family (Probable). Regulates endosome recycling downstream of rab-10 and upstream of arf-6 (PubMed:22869721)",
            "Promotes apoptosis during embryonic development. Produced by caspase ced-3-mediated cleavage, and translocates to the plasma membrane where it prevents the activation of the prosurvival Akt-1/2 and sgk-1 signaling pathway by competing with Akt-1/2 for the binding to PtdIns(3,4,5)P3"
        ],
        "length": 826,
        "sequence": "MTVSNNGMAMPSVPPKIDCSEAIQDSPKFRATVAQHAMYFNRLENRLNEMLRHITAMIDFSKNYTNTFYKLTVSVNQLCDESFSGNPLASTTFQGLSEAYAHTVNLFRTYFDHSNVVTFTKLSNFIKIELTKVAESRAHFENMSQSMDDALVKNASISRQKPADATEGRNALTAVGTCFAHTTLDYVANINIAHAHKDHMILDALWTLVRESSAFFSKGHATFDEWTAADNGAIADTIQTFAAKSKLIERKMQDVHSLVPKEMFQHPSGMPIEPDVMMEGYLYKRSSNAFKTWNRRWFQIKDKQLLYSHRSTDLEPATIMEENLRICLVRPAPSNIDRIGCFELVTPTRIHLLQADSESLCQDWMRALQRTILALHEGDSVDVASTSPRNKTTSMSSGVTLTSANAISPLSNAMDVTKGRSVSDPASTYTSANTSSISTAAGFSSSTTAFEQVRRVPGNEVCADCGSPAPKWVSINLGVVLCIECSGAHRSLGVQTSKVRSLCMDSIDNELRDVLLALGNRQVNEIFLAHLPPADSIVPPQINEKSARPAREAWIKAKYVERRFAVAEDTRARSSATNRQEHLKHKTSIGGNSSSNGVNRSSSYADVQDAESGGLLDADPWSADLSVPVPTASKRLSACGSDTNLDAIGSSSIDTKTVEWDSVKEACECGDLLALMTAYAQGFDLNALHNGTTALHIATRNGQTAAVEFLLLNGAKINMLDEKLNTPLHLAAKEGHTLPVCQLLKRGADSNLANVDSKTPLDIAMECTHADIVTLFRVTIMRNDFNADFNNPMDETVEAVISDIARRAATEKEQKKTESLKSTSDI",
        "proteome": "UP000001940",
        "gene": "cnt-1",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005737",
                "name": "cytoplasm",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0005096",
                "name": "GTPase activator activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "09c67d4ad963853f9bf4e773ddc398d162b76d4e",
        "counters": {
            "domain_architectures": 7550,
            "entries": 34,
            "isoforms": 2,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 4,
                "ssf": 4,
                "pfam": 4,
                "cdd": 3,
                "profile": 4,
                "smart": 3,
                "panther": 1,
                "prints": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 7550
        }
    }
}