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InterPro-Version: 108.0
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{
"metadata": {
"accession": "Q9X1X0",
"id": "MRE11_THEMA",
"source_organism": {
"taxId": "243274",
"scientificName": "Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)",
"fullName": "Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)"
},
"name": "DNA double-strand break repair protein Mre11",
"description": [
"Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair (PubMed:21458667, PubMed:21937514, PubMed:24316220). The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA (By similarity). Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity (Probable) (PubMed:20122942, PubMed:21458667, PubMed:24316220)"
],
"length": 385,
"sequence": "MINLKELKILHTSDWHLGVTSWTSSRPVDRREELKKALDKVVEEAEKREVDLILLTGDLLHSRNNPSVVALHDLLDYLKRMMRTAPVVVLPGNHDWKGLKLFGNFVTSISSDITFVMSFEPVDVEAKRGQKVRILPFPYPDESEALRKNEGDFRFFLESRLNKLYEEALKKEDFAIFMGHFTVEGLAGYAGIEQGREIIINRALIPSVVDYAALGHIHSFREIQKQPLTIYPGSLIRIDFGEEADEKGAVFVELKRGEPPRYERIDASPLPLKTLYYKKIDTSALKSIRDFCRNFPGYVRVVYEEDSGILPDLMGEIDNLVKIERKSRREIEEVLRESPEEFKEELDKLDYFELFKEYLKKREENHEKLLKILDELLDEVKKSEA",
"proteome": "UP000008183",
"gene": "mre11",
"go_terms": [
{
"identifier": "GO:0016787",
"name": "hydrolase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004519",
"name": "endonuclease activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0008408",
"name": "3'-5' exonuclease activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006259",
"name": "DNA metabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "ef5c77ef2f5507aabdab8fcda639d0d1754eb940",
"counters": {
"domain_architectures": 5,
"entries": 17,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 14,
"taxa": 1,
"dbEntries": {
"cathgene3d": 3,
"pfam": 3,
"ssf": 1,
"cdd": 1,
"panther": 1,
"ncbifam": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 5
}
}
}