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InterPro-Version: 108.0
InterPro-Version-Minor: 0
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{
"metadata": {
"accession": "Q9MZU5",
"id": "Q9MZU5_PIG",
"source_organism": {
"taxId": "9823",
"scientificName": "Sus scrofa",
"fullName": "Sus scrofa (Pig)"
},
"name": "Intercellular adhesion molecule 1",
"description": [
"ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation"
],
"length": 537,
"sequence": "MAPGATHPGQLALLALLLPLLGALLPGLGGAEISMWPLNTIIPKGGSMKVNCSVACDGNITSFGLETHWHKTEVDHRDKWKIFELSNVENDGTLLCHAVCQGNQTQVQGNLTVYWFPEYVKLANLSWQREGQHFNLSCQVSGGAPRTNLSAVLFRGEEELFRQSVGMEEPANVTFRMLASRKDHGANFSCRTELNLQPQGLELFWNSSAPLKLQTYVLPATHPHLATPELVEVGTPVSVNCSLDGLFPASEATVHLARGDHRPPLTITHNGDSLLAKTWINGTEKEQGTQYLVCEIMLADEKVVTKKNVTFYSFPPPNLTLSEPEVSEGTTVSIECQAHGEAVVTLNEVPAEPPSQRAQLKLNVSAEDHGRSFSCSAALTVAGHVLYKNQTQVLSVLYGPRLDERDCPGNWTWPEGSHQTLTCQARGNPTPKLICRREGDGALLPTGDLGPVKREITGTYQCQATSSRGVATRVVVVNVIHNQNNMVIIIPVAAVAILGSVGVAAYIYNYQRKIQKYELQKAQENAAMKLSTPASPP",
"proteome": null,
"gene": "ICAM-1",
"go_terms": [
{
"identifier": "GO:0005178",
"name": "integrin binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0007155",
"name": "cell adhesion",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0098609",
"name": "cell-cell adhesion",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 2,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "176d6d905b5d01023d24484f892bed30f7432200",
"counters": {
"domain_architectures": 94,
"entries": 19,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 3,
"ssf": 1,
"cathgene3d": 1,
"smart": 1,
"profile": 1,
"panther": 1,
"prints": 2,
"interpro": 9
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 94
}
}
}