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{
    "metadata": {
        "accession": "Q6DEU3",
        "id": "VPS29_XENTR",
        "source_organism": {
            "taxId": "8364",
            "scientificName": "Xenopus tropicalis",
            "fullName": "Xenopus tropicalis (Western clawed frog)"
        },
        "name": "Vacuolar protein sorting-associated protein 29",
        "description": [
            "Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). Component of the retriever complex, which is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos (By similarity). Component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. In the endosomes, retriever complex drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to snx17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling (By similarity). The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes (By similarity)"
        ],
        "length": 182,
        "sequence": "MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESFDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQLDVDILISGHTQKFEAFEHENKFYINPGSATGAYNALENNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS",
        "proteome": "UP000008143",
        "gene": "vps29",
        "go_terms": [
            {
                "identifier": "GO:0042147",
                "name": "retrograde transport, endosome to Golgi",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0030904",
                "name": "retromer complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "045f46c6dd3b00ff866eb37d34d31f5ff8a68e69",
        "counters": {
            "domain_architectures": 33829,
            "entries": 10,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 1,
                "ssf": 1,
                "cathgene3d": 1,
                "cdd": 1,
                "ncbifam": 1,
                "panther": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 33829
        }
    }
}