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{
    "metadata": {
        "accession": "Q6C8R5",
        "id": "CTU1_YARLI",
        "source_organism": {
            "taxId": "284591",
            "scientificName": "Yarrowia lipolytica (strain CLIB 122 / E 150)",
            "fullName": "Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast)"
        },
        "name": "Cytoplasmic tRNA 2-thiolation protein 1",
        "description": [
            "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation"
        ],
        "length": 365,
        "sequence": "MLCVLCECRKAMLKRPKTLQPICKPCFYNVFETEIHNTIVESNLFFPGERVAIGASGGKDSTVLAHVMKTLNERYNYGVDFVLLSIDEGIHGYRDDSLETVKRNKVQYDMDLEVVSYSELYGWSMDQIVAQIGNKNNCTYCGVFRRQALDRGSAKLGIAHIVTGHNADDMAETVLMNLLRGDTARLDRCTELVTGSDDSPVKRSKPLKYAYEKEIVLYAHYKKLDYFSTECTYSPEAFRGTARTLIKNLEAIRPSTIIDIIHSGEAFVLKKKKEKKGKGSVVVKAKVEEKPVPSGGCSVPLAFDSSLGLSNRCTKCGYLSHNAVCKACVLLEGLNAGRAKMQIEGDSADGAAKNIKTLEKLALSI",
        "proteome": "UP000001300",
        "gene": "NCS6",
        "go_terms": [
            {
                "identifier": "GO:0008033",
                "name": "tRNA processing",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0000049",
                "name": "tRNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0002098",
                "name": "tRNA wobble uridine modification",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0034227",
                "name": "tRNA thio-modification",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "ecea3fd540da2a3be05a58e475a5fac2d5801c14",
        "counters": {
            "domain_architectures": 3042,
            "entries": 16,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "cdd": 1,
                "pfam": 2,
                "pirsf": 1,
                "hamap": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 3042
        }
    }
}