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{
    "metadata": {
        "accession": "Q5WPU9",
        "id": "YP11_LUTLO",
        "source_organism": {
            "taxId": "7200",
            "scientificName": "Lutzomyia longipalpis",
            "fullName": "Lutzomyia longipalpis (Sand fly)"
        },
        "name": "Yellow-related salivary protein LJM11",
        "description": [
            "Probably modulates blood feeding of sand flies on vertebrate species by binding and sequestering different mediators involved in the host response (Probable). Binds biogenic amines (PubMed:21795673). Binds serotonin with high affinity (PubMed:21795673, PubMed:31604119). Binds adrenaline and noradrenaline (PubMed:21795673, PubMed:31604119). Binds dopamine and octopamine (PubMed:21795673, PubMed:31604119). Poorly binds histamine (PubMed:31604119). Induces a delayed type hypersensitivity response in host tissues (PubMed:21795673). Induces systemic Th1 immune response in the host (PubMed:21795673, PubMed:22739793, PubMed:29037520). Immunogenic; elicits antibody production in the host (PubMed:21795673, PubMed:29037520). Functions as a chemoattractant for host neutrophils; likely acts through a G-protein-coupled receptor and effect is dependent on calcium influx (PubMed:34050141)",
            "(Microbial infection) Modulates infection caused by Leishmania species in the host"
        ],
        "length": 399,
        "sequence": "MKVFFSIFTLVLFQGTLGADTQGYKWKQLLYNNVTPGSYNPDNMISTAFAYDAEGEKLFLAVPRKLPRVPYTLAEVDTKNSLGVKGKHSPLLNKFSGHKTGKELTSIYQPVIDDCRRLWVVDIGSVEYRSRGAKDYPSHRPAIVAYDLKQPNYPEVVRYYFPTRLVEKPTYFGGFAVDVANPKGDCSETFVYITNFLRGALFIYDHKKQDSWNVTHPTFKAERPTKFDYGGKEYEFKAGIFGITLGDRDSEGNRPAYYLAGSAIKVYSVNTKELKQKGGKLNPELLGNRGKYNDAIALAYDPKTKVIFFAEANTKQVSCWNTQKMPLRMKNTDVVYTSSRFVFGTDISVDSKGGLWFMSNGFPPIRKSEKFKYDFPRYRLMRIMDTQEAIAGTACDMNA",
        "proteome": "UP000092461",
        "gene": null,
        "go_terms": null,
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "64050879111ddb5de47221b04285dccc99ab9733",
        "counters": {
            "domain_architectures": 8869,
            "entries": 6,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 1,
            "structures": 3,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "interpro": 2
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 8869
        }
    }
}