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{
    "metadata": {
        "accession": "Q56R14",
        "id": "TRI33_XENLA",
        "source_organism": {
            "taxId": "8355",
            "scientificName": "Xenopus laevis",
            "fullName": "Xenopus laevis (African clawed frog)"
        },
        "name": "E3 ubiquitin-protein ligase TRIM33",
        "description": [
            "Acts as an E3 ubiquitin-protein ligase for smad4. Promotes ectoderm embryonic development at the expense of other germ layers. Inhibits mesodermal differentiation. Promotes neural development of the ectoderm. Promotes smad4 alpha degradation via the ubiquitin proteasome pathway. May act as a transcriptional repressor (By similarity)"
        ],
        "length": 1091,
        "sequence": "MADNKGGGGGGGETEGDASSNNNNNSNGAGETGSPGETESQAVEEPESAEKAPVAAVPTDTPAEENPAPSSSSVASSSATPASSSSSPLVVNLLDTCAVCKLSLQSRDTEPKLLPCLHSFCRRCLPEPERQLSVPGGTNGDIQQVGVIRCLVCRQECRQIDLVDNYFVKDASEAPNTDEKSEQVCTSCEDNASAVGFCVECGEWLCKTCIEAHQRVKFTKDHIITNKEDVSSESVGASGQRPVFCPVHKQEQLKLFCETCDRLTCRDCQLLEHKEHRYQFLEEAFQNQKGAIENLLAKLLEKKNYVHFAATQVQNRIKEVNETNKRVEQEIKVAIFTLINEINKKGKSLLQQLESVTKERQIKLVQQQNDITGLSRQIKHVMTFTNWAIASGSSTALLYSKRLITFQLRHILKARCDPVPAANGAIRFHCDPTFWAKNVVNLGNLVIENKPTTGFTPNVVVGQVPQGANHVNKPPAQINLAQLRLQHMQQQVYAQKQQQLQMRMAQPPGQHQRPSAPQVMHQQPPRLISMQSMPRNNMNCGPFQAHQMRMAQNAAQNAARMSGVPRHNGMQYSMMQPHLQRQHSNPGHAGPFPVVSVHNNTINPTSPTTATMANANRGPTSPSVTSIELIPSVTNPENLPSLPDIPPIQLEDAGSSNLDNLLSRYISLGHQLPQPTSNMNPSPAPSAMSPGSTGLSNSHTPVRPPSTSSTGSRGSCGSSSRTVERNSSFKSDPVKVKQEPGTEEEVCSFSGPVKQEKAEDGRRSACMLSSPESSLTPPLTTNVHLETDLESLAALENNVKTEPNNTSQSCRQSSHVSLVNGKSAVRNSMHRPPRGGGGGDGSNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGEWICTFCRDLNKPEVEYDCDNSQHSKKGKTVQGLSPVDQMKCERLLLYLYCHELSIEFQEPVPATIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQTPEDFVADVRLIFKNCERFNEMMKVVQAYADTQEINLQNDSEVAQAGKAVVLYFEEKLPAIYPDRTFQPLPEFEAEDDDGDVTDDSDDDDFVQPRRKRLKSEERPVHIK",
        "proteome": "UP000186698",
        "gene": "trim33",
        "go_terms": [
            {
                "identifier": "GO:0008270",
                "name": "zinc ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 1,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "08956d4791678d6bbb778d921445b38e634a00aa",
        "counters": {
            "domain_architectures": 2080,
            "entries": 39,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 5,
                "ssf": 4,
                "cathgene3d": 4,
                "smart": 5,
                "profile": 4,
                "pfam": 3,
                "panther": 1,
                "prosite": 2,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2080
        }
    }
}