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InterPro-Version: 108.0
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{
"metadata": {
"accession": "P42412",
"id": "IOLA_BACSU",
"source_organism": {
"taxId": "224308",
"scientificName": "Bacillus subtilis (strain 168)",
"fullName": "Bacillus subtilis (strain 168)"
},
"name": "Malonate-semialdehyde dehydrogenase",
"description": [
"Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively (PubMed:16332250, PubMed:18310071, PubMed:21515690). Is involved in a myo-inositol catabolic pathway (PubMed:18310071). Bicarbonate, and not CO2, is the end-product of the enzymatic reaction (PubMed:16332250)"
],
"length": 487,
"sequence": "MAEIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFKTWSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALGEVGRGIENVEFAAGAPSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSERTPLLTEKLVELFEKAGLPKGVFNVVYGAHDVVNGILEHPEIKAISFVGSKPVGEYVYKKGSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGIADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGRENVSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFTSNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDFYTRKKVVTARYPAPDFN",
"proteome": "UP000001570",
"gene": "iolA",
"go_terms": [
{
"identifier": "GO:0016491",
"name": "oxidoreductase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004491",
"name": "methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "dd09ddecf5caaba5fcfea9e2a4f53107ee48a6df",
"counters": {
"domain_architectures": 359073,
"entries": 16,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 1,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"cdd": 1,
"cathgene3d": 2,
"hamap": 1,
"panther": 1,
"ncbifam": 1,
"pfam": 1,
"prosite": 1,
"interpro": 7
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 359073
}
}
}