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InterPro-Version: 108.0
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{
"metadata": {
"accession": "P09703",
"id": "US27_HCMVA",
"source_organism": {
"taxId": "10360",
"scientificName": "Human cytomegalovirus (strain AD169)",
"fullName": "Human cytomegalovirus (strain AD169) (HHV-5)"
},
"name": "G-protein coupled receptor homolog US27",
"description": [
"Interacts with the host Gi complex without activating it, thereby probably interfering with the chemokine-Gi signaling (PubMed:35061538). May also function as a G protein sink to sequester G protein from the cell surface via internalization (PubMed:35061538). Plays an important role in spread of HCMV via the extracellular route"
],
"length": 362,
"sequence": "MTTSTNNQTLTQVSNMTNHTLNSTEIYQLFEYTRLGVWLMCIVGTFLNVLVITTILYYRRKKKSPSDTYICNLAVADLLIVVGLPFFLEYAKHHPKLSREVVCSGLNACFYICLFAGVCFLINLSMDRYCVIVWGVELNRVRNNKRATCWVVIFWILAVLMGMPHYLMYSHTNNECVGEFANETSGWFPVFLNTKVNICGYLAPIALMAYTYNRMVRFIINYVGKWHMQTLHVLLVVVVSFASFWFPFNLALFLESIRLLAGVYNDTLQNVIIFCLYVGQFLAYVRACLNPGIYILVGTQMRKDMWTTLRVFACCCVKQEIPYQDIDIELQKDIQRRAKHTKRTHYDRKNAPMESGEEEFLL",
"proteome": "UP000008992",
"gene": "US27",
"go_terms": [
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0004930",
"name": "G protein-coupled receptor activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0007186",
"name": "G protein-coupled receptor signaling pathway",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 1,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": false,
"in_bfvd": false,
"ida_accession": "587fa3dbe4504dc051049f3cca904dd9ab631b87",
"counters": {
"domain_architectures": 394800,
"entries": 10,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 2,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"profile": 1,
"pfam": 1,
"panther": 1,
"prosite": 1,
"prints": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 394800
}
}
}