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{
    "metadata": {
        "accession": "K9J2K2",
        "id": "K9J2K2_DESRO",
        "source_organism": {
            "taxId": "9430",
            "scientificName": "Desmodus rotundus",
            "fullName": "Desmodus rotundus (Vampire bat)"
        },
        "name": "Epithelial splicing regulatory protein 2",
        "description": [
            "mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2"
        ],
        "length": 717,
        "sequence": "MTPPPPQPPPPGPNPAADSAADPHPEPGPLVVLFGATAGALGPDLGSDETDLILLVWQVVEPRSRQVGTLHKSLIRAEAAALSSQCREASGLSADSLARAEPLDKVLLQFSQLVSGDIALLGGGPYVLCTDGQQLLRQVLHPEASRKNLVLPDTFFSFYDLRREFHVEHPSTHLARDLTVATMAQELGLETDATEDDFGVWEVKTMVAVILHLLEGPSGQLFSKPEVIKQKYETGPCSKADVVDSETVVRARGLPWQSSDQDVARFFKGLNIARGGVALCLNAQGRRNGEALIRFVDSEQRDLALQRHKHHMGVRYIEVYKATGEEFVKIAGGTSLEVARFLSREDQVILRLRGLPFSAGPADVLEFLGPECPVTGGADGLLFVRHPDGRPTGDAFALFACEELAQAALRRHKGMLGKRYIELFRSTAAEVQQVLNRYASSPLLPTLTAPLLPIPFPLAAGTGRDCVRLRGLPYTATIEDILSFLGEAAADIRPHGVHMVLNQQGRPSGDAFIQMTSAERALAAAQRCHKKVMKERYVEVVPCSTEEMSRVLMGGTLGRSGMSPPPCKLPCLSPPAYATFQATPTLIPTETAALYPSSALLPAARVPAAPTPVAYYPGPATQLYMNYTAYYPSPPVSPTTVGYLTTPSAALASAPTSVLSQPGALVRMQGVPYTAGMKDLLSVFQAYQLVPDDYTSLMHVGDPSRTVLQAPKEWVCL",
        "proteome": null,
        "gene": null,
        "go_terms": [
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 2,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "bdf827d8b90aca965ea063a4255bf4b88713344d",
        "counters": {
            "domain_architectures": 5755,
            "entries": 14,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "smart": 1,
                "pfam": 1,
                "cdd": 1,
                "panther": 1,
                "interpro": 6
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 5755
        }
    }
}