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{
    "metadata": {
        "accession": "J4UJF5",
        "id": "SIDD_BEAB2",
        "source_organism": {
            "taxId": "655819",
            "scientificName": "Beauveria bassiana (strain ARSEF 2860)",
            "fullName": "Beauveria bassiana (strain ARSEF 2860) (White muscardine disease fungus)"
        },
        "name": "Nonribosomal peptide synthetase SIDD",
        "description": [
            "Nonribosomal peptide synthetase; part of the gene cluster that mediates the biosynthesis of at least 11 siderophores, including beauverichelin A, dimerumic acid (DA), Na-dimethyl coprogen (NADC), eleutherazine B, ferricrocin (FC), fusarinine A, fusarinine C (FsC), metachelin A, mevalonolactone, rhodotorulic acid (RA) and tenellin (PubMed:39109629). This cocktail of siderophores for iron metabolism is essential for virulence, and more specifically for the fungal virulence in penetrating through the host cuticle (PubMed:39109629). Siderophore synthesis is also involved in conidial germination under iron-deficient conditions (PubMed:39109629). SIDC catalyzes the assembly of ferricrocin whereas SIDD catalyzes the assembly of fusarinine C (PubMed:39109629)"
        ],
        "length": 1843,
        "sequence": "MLSIDDHGGGGPLAVDIIPAGSGAQKTAPDAADPSLHGPGRANGDAVNADATAAEETGSRDDESQQQQQQQQQQQQQQQQQRSLLSERDLDQLWQWNAVVPETIQRCIHDIISEQAAQRPQDVAVQSWDGSLTYSELEHLSTQLALHLRLLGVDIGVTVPLCFEKSKWTVVALLAVMKAGAAFSLTDPSQPEARLQTIVEQTGAKLLVTSALQSSLGAKIAPGATVVAVSQATFDTPLQQSSDPLPDVPSSSLMYVIFTSGSTGKPKGVSISHENFTSGAIPRAEAVGYKSTSRVFDFPSYAFDVSIDCMLCTLACGGQVCVPSEQGRMNDLSGSIRDSKANMVHMTPSVARVLDSDIIPSLDVLGLGGEVVSGSDAATWRQFTHLIIGYGPSECTVGCTVNNNTSLSTGIGKGVGCVMWLVDPEDHNVLVPVGEVGELLIEGPVVGIGYLGEPAKTAEVFIEDPTWLTAGHGCYAGRHGRLYKTGDLVRYEDNLSGSIEFVGRKDQQVKIRGQRVELTEVEHHIQTCLPTGVKVVAEVIKPENASPTLVAFLAEKSSVGSQDGSLFVDPSPELSAALDKIDTTLGAKVPKYMIPAAFITLASMPTMVSMKTDRKKLREIGISIPRSKLGATHADEGPQEEPETDAEKKLAHAWQLVLASSSPVYKASSFFGLGGDSLRAMKLVSAAREQGLGLTVADIFNNPTLSAMANKSTSISSATQEQVKPFSLLQEGWDEQTARKDVAELCGIEPEQVEDVYPCTPLQEGLMALSSKVKEAYIAQRVVVLKDLETAKRLMAAYDEASRGSPILRTRIVQVPRRGLMQVVVNRKLEYTTGNNVAAYLASDRETPMDLGTALWRYAIITDEAAGTVSFVLTMHHALYDGWSMPLVVERINQAYQHPGKPLSRPSEFKDFIKYLLSQDAAESEKYWRAQLEGAHRLQFPLLPHQGYQTAADELLEEYVPLEQLPKNATVATLIRAAWAIVASQYINSTDVVFGETLTGRNAPVVGVDEIEGPMITTVPLRVPVDAEAQVGEFLQAIQEQTVGQIPHEHFGLQHIRRLSPDAREACELRAGLVLHPSADTAAPEVDATLPANNLIPHLAAREALKFNTFALMLVCSMDPKGFQVMASFDSKMVDKSTMRRALAQFKSVAQQLAQSTTTLLGNVRALSDDDAAALRDVVATAQEDPVVKTYDGASAAYIVRSDDASKMVPVGAIGELAIQTSQPKDLSTLPVPSWLAALLPPSAPTDALYLTGKLARYDAAGKIQVLGDKASLTASTDASAAARKPRVSATSQRQRRLRALWSHVLRTPETEIGLDDSFFLLGGDSISAMKLASEARPEGIRLTVAQMFSHKTLAEMAAVMECTDESSDSTAAAAAEAPIAPIAEPFELLDGLVDDKSAFLANVVKPQLQDASWTVSNVLPTRFLQELTVRATISKPRFAVRYELIFFDGPVDLRRLRQSCQRLVAHNEILRTVYVESADRIYAAVLDALETPFEEFAYTNPAVDLSTFTKDICRADVDKPQPLGSSFVKWLYVADPQRPAARSCLVFRMSHAQYDEMCLPIMLRQLSALYAHDKTPEPSVPFSAYVSHVMRTAVPASLPYWRELLAGSTITSFRPDIPITDRRHAAIAQTVDISARTRDVTLASLPTATWALCLARRRALRDVVFGEVVSGRNVGLPGAESIAGPCWQYVPLRVRFDPSWTGNDLLAFVQQQHVESAGHEAVSLREIAENCGLGWEKQASMPGDDRPAQWWFDTVCHQDVSHVKERENTDEEAQTKYETLYTDEEPLREWKVQTYVRDGGNSVVLEVVTFKSWEEHGKGLLADLVKAMEQLVHRPGEKLFSD",
        "proteome": "UP000002762",
        "gene": "SIDDA",
        "go_terms": [
            {
                "identifier": "GO:0031177",
                "name": "phosphopantetheine binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003824",
                "name": "catalytic activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "reviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "659a8cb03cf64c213c74da57ad63126e139952a4",
        "counters": {
            "domain_architectures": 427,
            "entries": 31,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 5,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 3,
                "cathgene3d": 5,
                "cdd": 3,
                "profile": 1,
                "smart": 1,
                "pfam": 3,
                "panther": 1,
                "ncbifam": 1,
                "prosite": 2,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 427
        }
    }
}