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{
    "metadata": {
        "accession": "I2H2P2",
        "id": "I2H2P2_HENB6",
        "source_organism": {
            "taxId": "1071380",
            "scientificName": "Henningerozyma blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7)",
            "fullName": "Henningerozyma blattae (strain ATCC 34711 / CBS 6284 / DSM 70876 / NBRC 10599 / NRRL Y-10934 / UCD 77-7) (Yeast)"
        },
        "name": "Integrase catalytic domain-containing protein",
        "description": [
            "Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome",
            "Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends"
        ],
        "length": 726,
        "sequence": "MPTLNTIKSAQSFLGMVNYYRNFIPQCSLLSKPIIEFISKKCDWSKKQDQAVITLKQKLCSAPVLVPFIPGDEYRLSTDASTIALGGVLERLGQLVGVIGYFSKTTQAHYPVGEIELLSIIQNLQHFKYYLHGHHFILRTDHISLLAYRNKKEPSARISRWLDFLAEFDFTLEYIKGSLNHVADALSRPATKNEITTNEVSKVAIIEKIEDPTLVFPINSIERITPVDWYEDWIQDPWSAAVLVHLGLIQDVKINPIDKSLFDKYIKKLKLSKKAMARYKFDDQILYYDDRVCVPCSRRTELLNIYHDNILHGGHFGEVTTINKICPNYYWPSMTVDIRTYIKGCLQCQIMKKFRPKKDGQLEPLDIPQGRWLELSIDFVTGLPTTQSQNDMIMVVVDRFSKRAHFIATQISLGSVGTLDLFYRFIFAYHGFPRTIASDRDIRFTSSFYKEVTERLGIKLLLSSSNHPQTDGQTESVNKTLGRLLRSYCSQDQDNWGHFLPQVEFVYNSTFQRSIRASPFEVDLGYIPNEPLLDIGNELLARNLSAVDLSKTIKAISLRTTDFLKQSQEDMESHANETRTVNDYKLGEYVLLHRDAYFTGGRYLKIQPIFLGPFKIVKIGKITIELDLPSSFKKHRVINIKWIKEFVLDKDRYPKSLPRTSIERIQRAQEIIAVIGYDVESHEYYCKMKDVDPTLTCTYSLEEFNKLTSSKKSSLLNNFNTLVNTN",
        "proteome": "UP000002866",
        "gene": "TBLA0D01360",
        "go_terms": [
            {
                "identifier": "GO:0003676",
                "name": "nucleic acid binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0015074",
                "name": "DNA integration",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "c6c5c7e2ffde1a4e14d5d0412cb5c4eb2924f4f3",
        "counters": {
            "domain_architectures": 2502,
            "entries": 17,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "ssf": 2,
                "pfam": 2,
                "cdd": 1,
                "profile": 1,
                "panther": 1,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 2502
        }
    }
}