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{
    "metadata": {
        "accession": "H6BPK3",
        "id": "H6BPK3_EXODN",
        "source_organism": {
            "taxId": "858893",
            "scientificName": "Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656)",
            "fullName": "Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) (Black yeast)"
        },
        "name": "Actin cytoskeleton-regulatory complex protein END3",
        "description": [
            "Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization"
        ],
        "length": 412,
        "sequence": "MSGSKRIEKWEIDRYWEIFSSLVQPPATSASHLTNQAAANVLRNSQLRDDQLERVWDLADVDGDGELDFEEFCVAMRLIFDLVNGEYQDVPKSLPDWLVPESKAHLVAANRALTGDRREQFERIEDDEDDAGLKDGFDWYMSPEDKHKYEEIYSANKDRRGEISFDSLQGLYASLDVPDTDIRSAWNLINTSGRDTISKDACLAFLHILNYRHEGYRIPRTVPPSLRASFEGNQIDYQIDSMRNRPNKYDEETPTGRKSKFGDAYLSRLGARGGSAYTPKGTDFSDVVEDEDLEKVRLLRELRELEAQHDAAIAAAERRRKQRQENGGGRQPGKTNWTLVKREAQQLLEYKRRQYLELNSETANKSGTDLKRLRDDLALVAEQIDGLESHLKKRQAELDNLRQEIENEKASR",
        "proteome": "UP000007304",
        "gene": "HMPREF1120_01794",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005509",
                "name": "calcium ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006897",
                "name": "endocytosis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0007015",
                "name": "actin filament organization",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "485a3a6bb3dfcff7f3bc3b18f8ddad09c4c2d1f8",
        "counters": {
            "domain_architectures": 1206,
            "entries": 16,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "smart": 2,
                "ssf": 1,
                "pfam": 2,
                "profile": 2,
                "cdd": 1,
                "panther": 1,
                "prosite": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1206
        }
    }
}