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{
"metadata": {
"accession": "H3A6M7",
"id": "H3A6M7_LATCH",
"source_organism": {
"taxId": "7897",
"scientificName": "Latimeria chalumnae",
"fullName": "Latimeria chalumnae (Coelacanth)"
},
"name": "ATP-binding cassette sub-family D member 3",
"description": [
"Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation"
],
"length": 658,
"sequence": "MAAFSRYLTAKNSSIAGAALLLLYLLNKRRGSSSSKKSGKTQVIQNNEKDGKKEKAVVDRVFFARIWTILKIMVPRMCSKESGYLLLIAAMLVARTYCDVWMIQNGTMIESGIISRNCKLFKEHFFRFTAAMPLISLINNFLKLGLNELKLRFRVRLTRYLYEEYLKGYTYYKMGNLDNRIANADQLLTQDVEKFCNSVVDLYSNLSKPLLDICLYIFKLTSAIGAQGPASMMAYLIVSGLFLTRLRRPIGKMTITEQRYEGEYRYVNSRLITNSEEIAFYNGNRREKQTIYTTFQKLVDHLHNFILFRFSMGFVDSIIAKYLATVVGYLVVSRPFLNLLHPRHMKSTHAELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNTGKYERTMISQQEKGTNAQQLQPLIPGSGRIYNLDNIIKFDHVPLATPNGDILIRDLSFEVKSGANVLVCGPNGCGKSSLFRVLGELWPLFGGNLTKPDRGKLFYVPQRPYMTLGTLRDQVIYPDTVEDQNRKGVTDQVLKEYLDNVQLGQILEREGGWDTVQDWMDVLSGGEKQRMAMARLFYHKPQFAILDECTSAVSVDVEDYIYSHCRKVGITLFTVSHRKSLWKHHEFYLHMDGRGKYDFKKITEETVEFGS",
"proteome": "UP000008672",
"gene": "ABCD3",
"go_terms": [
{
"identifier": "GO:0005524",
"name": "ATP binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0140359",
"name": "ABC-type transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0055085",
"name": "transmembrane transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016887",
"name": "ATP hydrolysis activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005324",
"name": "long-chain fatty acid transmembrane transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0042626",
"name": "ATPase-coupled transmembrane transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0015910",
"name": "long-chain fatty acid import into peroxisome",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0005777",
"name": "peroxisome",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "7d63b8933b00a43572cacec89714035b15328362",
"counters": {
"domain_architectures": 17112,
"entries": 21,
"isoforms": 0,
"proteomes": 1,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"ssf": 2,
"profile": 2,
"cdd": 1,
"pfam": 2,
"smart": 1,
"panther": 1,
"ncbifam": 1,
"prosite": 1,
"interpro": 8
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 17112
}
}
}