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{
    "metadata": {
        "accession": "H2T1W4",
        "id": "H2T1W4_TAKRU",
        "source_organism": {
            "taxId": "31033",
            "scientificName": "Takifugu rubripes",
            "fullName": "Takifugu rubripes (Japanese pufferfish)"
        },
        "name": "Platelet-derived growth factor receptor beta",
        "description": [
            "Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells"
        ],
        "length": 1117,
        "sequence": "MFFANSEGVRRVGSSMLRASAMRAAVLHLTVALAALLSSCTTVSCLKIVPEEKQLILAEGSSLSLTCAGSSETTWDLKSDDVPFFQMKAESSDLNYKIVQSNSTASVLTLWHVDWKNTAVYQCREQLTGEIKEVAVFVPDPEVWFIESSHGMVTKTSGESTVPCVVTNPNITVTLYDKDTDLPVNGVYVPSEGFKAYLDYRTYVCRGELNGEVKESQAFNVYSIHVPEDIDAYVNASQTVLKQGEPLTVNCTVQGVELVLFSWDIPNRDIVKHKPETVVLSATTMRSCLVFPHATVAHSGTYVCHAHESTQDQKAFASVNITVLERGFVAVKSTKKQNITAELQENVELRVEIEAYPPPQIRWKKDGAPVRGDKTIIIRQEHEIRYVTILTLVRVRTEQKGLYTALITNEDDVKEVTFALEVQVLARIKDLTDHHLPGKKQLVTCVAEGVPTPTIQWYSCDSMLKCNNQTSLWQQLKADPELLSIHTSVTEARRTNQVRSQVTFFKPQHTTVRCETTNQEGLIDFRDVKLVSSSLFSQVVLLAVVLTLVPIIIMSIIILIAVWKKKPRYEIRWKVIESVSQDGHEYIYVDPIHLPYDLAWEMPRDNLVLGRTLGSGAFGRVVEATAHGLSHSQSSIKVAVKMLKATARRSETQALMSELKIMSHLGPHLNIVNLLAACTKHGPLYLVTEYCRYGDLVDYLHRNKHTFLQYYLDKNQDDGSLISGGSTPLSQRKGYVSFGSESDGGYMDMSKDEPAVYVPMQEQMDTIKYADIQPSPYESPYQQDLYQEQGGGRVDLVISDSPALTYDDLLGFSYQVAKGMEFLASKNCVHRDLAARNVLICEGKLVKICDFGLARDIMHDSNYISKGSTFLPLKWMAPESIFHNLYTTLSDVWSYGILLWEIFTLGGTPYPDLPMNELFYSALKRGYRMAKPAHASDEVYEIMKRCWDETFEKRPDFSFLVHCVGDMLTDSYKKKYSQVNETFLKSDHPAVARTKPRLSSPFPIANPAFGSPSLVGLSDFPDPYNQNTRRFRNEAEVQEGVTSFNEYIIPIPDPKPEEAFTDVPSESPESSLALEEETDSVHDSTDTLPEEDRLEETSERDALLGSSGTPEVEDSFL",
        "proteome": "UP000005226",
        "gene": "pdgfrb",
        "go_terms": [
            {
                "identifier": "GO:0004713",
                "name": "protein tyrosine kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005019",
                "name": "platelet-derived growth factor beta-receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0048008",
                "name": "platelet-derived growth factor receptor signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "98ab27ebcd0c4322765c7ba7a803e74b9844fb75",
        "counters": {
            "domain_architectures": 95,
            "entries": 34,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "profile": 2,
                "smart": 3,
                "ssf": 2,
                "pfam": 4,
                "pirsf": 2,
                "panther": 1,
                "prints": 1,
                "prosite": 2,
                "interpro": 14
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 95
        }
    }
}