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{
"metadata": {
"accession": "H2P541",
"id": "H2P541_PONAB",
"source_organism": {
"taxId": "9601",
"scientificName": "Pongo abelii",
"fullName": "Pongo abelii (Sumatran orangutan)"
},
"name": "Metalloendopeptidase",
"description": [
"Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding"
],
"length": 436,
"sequence": "MEGVGGLWPWVLGLLSLPGVILGAPLASSCPGACGTSFPDGLTPEGTQASGDKDIPAINQGLIPEETPESSFLIEGDIVRPSPFRLLSATSNKWPTGGGGVVEVPFLLSSKYGECKYDEPNRQVILEALAEFERSTCIRFVAYQGQRDFISIIPMYGCFSSVGRSGGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHARADRDRYIRVNWNEILPGFEINFIKSRSSNMLTPYDYSSVMHYGRLAFSRRGLPTITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSGPRPRGRGSHAHSTGRSPTPASLSLQQLLEALSAESRSPDPSGSSARGQPIPAGPGESPRGWESPALKKLSAEASARQPQTLASSSRSRPGVGAPGVAQEQSWLAGVPTEPTVPSSEAGIQPVPVQGSPALPGGCVPGNHFKGRSED",
"proteome": "UP000001595",
"gene": "ASTL",
"go_terms": [
{
"identifier": "GO:0008237",
"name": "metallopeptidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004222",
"name": "metalloendopeptidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006508",
"name": "proteolysis",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0008270",
"name": "zinc ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "efeb0259b28ed197c93a8972de3a29c21620a393",
"counters": {
"domain_architectures": 19101,
"entries": 10,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"profile": 1,
"smart": 1,
"ssf": 1,
"pfam": 1,
"panther": 1,
"prints": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 19101
}
}
}