HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "H0WZ29",
"id": "H0WZ29_OTOGA",
"source_organism": {
"taxId": "30611",
"scientificName": "Otolemur garnettii",
"fullName": "Otolemur garnettii (Small-eared galago)"
},
"name": "Pseudouridylate synthase 1 homolog",
"description": [
"Pseudouridylate synthase that catalyzes pseudouridylation of tRNAs and mRNAs. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Also catalyzes pseudouridylation of mRNAs: mediates pseudouridylation of mRNAs with the consensus sequence 5'-UGUAG-3'. Acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing. Involved in regulation of nuclear receptor activity through pseudouridylation of SRA1 mRNA"
],
"length": 384,
"sequence": "PSDRKARGGWPGGTRTWEDSEHQAKKLRGSEEEPRPRLPKRKIVLLVAYAGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMSFQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNKCDARTYCYMLPTFAFAHKDRDVQDETYRLSPETLQRVNRLLACYKGTHNFHNFTSQKGPREPSAQRYILEMFCEEPFEREGLEFAVIKVKGQSFMMHQIRKMVGLVVAIVKGYAPESVLERSWGEEKVDVPKAPGLGLVLERVHFEKYNQRFGNDGLHEPLDWAQEEGKVAAFKEEHIYPTIVSTERDERSMAQWLSTLPVHDFSATALAAAGTGTKASSPQEGSGGDEDTD",
"proteome": "UP000005225",
"gene": null,
"go_terms": [
{
"identifier": "GO:0003723",
"name": "RNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0009982",
"name": "pseudouridine synthase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0001522",
"name": "pseudouridine synthesis",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0009451",
"name": "RNA modification",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0031119",
"name": "tRNA pseudouridine synthesis",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "19256404772d8c42f87a117f633a8ad0cab47de9",
"counters": {
"domain_architectures": 18208,
"entries": 13,
"isoforms": 0,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 2,
"ssf": 1,
"cdd": 1,
"pfam": 1,
"panther": 1,
"ncbifam": 1,
"interpro": 6
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 18208
}
}
}