General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "H0WQU5",
        "id": "H0WQU5_OTOGA",
        "source_organism": {
            "taxId": "30611",
            "scientificName": "Otolemur garnettii",
            "fullName": "Otolemur garnettii (Small-eared galago)"
        },
        "name": "Thioredoxin reductase 3",
        "description": [
            "Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components"
        ],
        "length": 595,
        "sequence": "RPPEDREEVRRRLMGLIEGNRVMIFSKSYCPYSTRVKELFSSLGIGCNILELDQIDDGANVQEVLSEISNQKTVPNIFVNKVHVGGCDRTFQAHQNGLLQKLLQEDSAYDYDLIVIGGGSGGLACAKEAAILGKKVMVLDFVVPSPQGTSWGLGGTCVNVGCIPKKLMHQAALLGQALHDSRKFGWEYNQHVRHSWETMIEAVQNHIGSLNWGYRLSLREKSVAYVNSYGEFVEHHKIKATNRKGQETCYTAAKFVIATGERPRYLGIQGDKEYCITSDDLFSLPHCPGKTLVVGASYVALECAGFLAGLGLEVTVMVRSVLLRGFDQEMAEKVGSYMEQHGVKFLRKFVPVMVQQLEKGSPGKLKVSAKSTEGPETIEGIYNTLLIFVISDPCTRKIGLEKIGVKINEKNGKIPVNDVEQTNVPYVFAIGDVLEGKPELTPVAIQAGKLLARRLFGAASEKCDYVNIPTAVFTPLEYGCCGLSEEKAVEAYKKENLEVFHSFFWPLEWTLAGRDNNTCYAKIICNKLDHDRIIGLHILGPNAGEVTQGFAAAMKCGLTKQQLDDTIGIHPTCGEVFTALEITKSSGLDITQKGC",
        "proteome": "UP000005225",
        "gene": null,
        "go_terms": [
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0050660",
                "name": "flavin adenine dinucleotide binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0045454",
                "name": "cell redox homeostasis",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004791",
                "name": "thioredoxin-disulfide reductase (NADPH) activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016668",
                "name": "oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "c6e7786c4de746e322561b18292160cad8bf5ee7",
        "counters": {
            "domain_architectures": 1152,
            "entries": 27,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 3,
                "profile": 1,
                "ssf": 3,
                "cdd": 1,
                "pfam": 3,
                "ncbifam": 2,
                "panther": 1,
                "prints": 2,
                "prosite": 1,
                "interpro": 10
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1152
        }
    }
}