General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "G8BVR8",
        "id": "G8BVR8_TETPH",
        "source_organism": {
            "taxId": "1071381",
            "scientificName": "Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5)",
            "fullName": "Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast)"
        },
        "name": "Serine/threonine-protein kinase RAD53",
        "description": [
            "Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5"
        ],
        "length": 845,
        "sequence": "MNGGTQPTQQATQATQKFLIDKFSQERIDDNIVCRVICTSGQIQIRDLRADIDQVIKEKQSIKKVWIFGRNPKCDYHLGDINRLSNKHFQLLLGEDGNLLIKDISTNGTWLNGEKLEKNRNQIISQGDEITVGLGVASDVLSLVLFINDKFAENLKNYKMNKSRASMDNGIEAGSSSKFQSSNIKSIKPLGIFKDFTIKDEVVGQGAFAIVKKAVERSTGKTFAVKIISKRKVMGNMDGVTRELEVLRKLDHPRIVRLKGFYEDEESYYLLMEFVSGGDLMDFVAAHGSVGEDAGREITRQILEAVKYIHSKCISHRDLKPDNILIEQDDPVLVKITDFGLAKVQGNGTFMKTFCGTLAYVAPEIISGSNNLEENEERNEYSSLVDMWSIGCLVYVILTGHLPFSGSTQEQLYKQVRNGSYHEGPLKDFRISDEARNFIDSLLQVNPNDRLSAERALQHPWIKMGYLNQSYNGSKTDSQLSQVSLSQSLSQQKILESMDDAQYEFMRQQKKLQMQKIKEEEEKEEEEKEEEFSASQFKGFKIPTRAPVQYMQPRATEFQQQRRIKKNNNNLFLTLHPLEESSIQESIEIKQGINPFFIGRTDDCNCRIEDNRLSKVHCFLLKNRHIVGNSFYESPAQGLDDIWYCHSGTNVSYINNVKIQAGYKRLLHDGDEIKIVWDKNHNFVIGFKVEINDTVGLFNDGSKPDNANDLQIVPQRADEQNLVTRLMQMMSMKRANNRQISSQQDVGLPQLQRNESDHTNDRVQDIVAPLSTDDQNLMDRLHQEPEFLSESVTPVKQVDGNTSNSNKLRRVHSVSLSQSQNDPNKKVKRAKLDPTEKNADNLQFI",
        "proteome": "UP000005666",
        "gene": "TPHA0G01600",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004672",
                "name": "protein kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006468",
                "name": "protein phosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0003688",
                "name": "DNA replication origin binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004712",
                "name": "protein serine/threonine/tyrosine kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000077",
                "name": "DNA damage checkpoint signaling",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006270",
                "name": "DNA replication initiation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006281",
                "name": "DNA repair",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0009202",
                "name": "deoxyribonucleoside triphosphate biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "992f871123a522edca7a45a82c1f6b3555621299",
        "counters": {
            "domain_architectures": 167,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "ssf": 2,
                "cathgene3d": 3,
                "smart": 2,
                "profile": 2,
                "pfam": 2,
                "pirsf": 1,
                "panther": 1,
                "prosite": 2,
                "interpro": 7
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 167
        }
    }
}