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{
    "metadata": {
        "accession": "G3UAB2",
        "id": "G3UAB2_LOXAF",
        "source_organism": {
            "taxId": "9785",
            "scientificName": "Loxodonta africana",
            "fullName": "Loxodonta africana (African elephant)"
        },
        "name": "Plexin-B1",
        "description": [
            "Receptor for SEMA4D. Plays a role in GABAergic synapse development. Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration"
        ],
        "length": 2125,
        "sequence": "MPVLGPALLQALWAGWVLALQPPPPAAFTPNGTQLQHLAQDPTSGTIYLGATNSLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQAQLTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLGQLLLRPERPGDTQYVAANDPVVSTVGLVAQDLAGDPLLFVGRGYTSRGVGGGIPPTTRALRPLDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRPYVSRVCLRDQHYYSYVELPLACQGGRYGLVQAAAVAMSGEVARGEVLFAAFSSAAPPAVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGAEVAYIEYDVNSDCAQLPVDTLDAYPCGSDHTPSPMASRIPLEATPVLEWPGVQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGQPYSTQTIQLGSAVSRDLTDGAFEHLYVMTQSTLLKVPVASCAQHLDCASCLTQRDPYCGWCVLLGRCSRRSECSRGQGPERWLWSFQPELSCLRVATVSPANISREERREIFLSVPDLPPLQPEESYSCHFGEHQSLAVLTSSGVKCHSPDPSESPALPKGADHVSVSVELRFGTVVIAQASLSFYDCVAVTELRLSAQCQACVSSRWGCNWCVWQHLCTHKALCDAGPMVVSQQSPLLSPAPSAGDVPTPFPPTTPKTAVTPAPDTLPMEPGAPSLATTSDTPPGARPSLLSPWGPGTGPGPIPAPTPTELPFREEPSPLGPHNRPGTAVSIPTVFGPTATPEDLLAPHPPPSDAAALPPVPADPGPENPPSVIPLDQPHGTAPATTFPGAVSSTRPALDWLTREGGELPEADEWTGGDTPAFSTSTLLSGDGDSAEHEGPPAPLILLSSLDYQYDTPGLWELEEVGWGASACPCVESVQGSMLMPVLVERQVHLLGRNLRLFQDSPGDTECVMELEGREWCLQLGLGPPPPASSKGLKLQLLVFLSYEALQPELRVELFLRRAGHLRIDSADGLHVVLYDCFVGHGDCSRCQTAMPQYGCVWCEGERPRCVAQEACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLGQHVQDVQDTVRVAGVPCAVDVQEYEVSSSLVCITGLSGEEVKGPATVEVPGRGHGVSEHYFAYQNPEVYSIFPARGPRAGGTCLTLHGSKLLTGHLEDIRVVVGDQLCHLLPEQQSEQLRCETSPHPAPATLPVAVWFGATERRLQHSQFQYTSDPNITSAGPAKSFLSGGREIRVRGQNLDVVQTPRIRVTVAPKALQPGQGLADPPLSSLPPHQFEEPCRVNSSQLITCRTPALPGLPESPWVQVEFVLDNLVFDFATLNSMPFSYEADPTLHPLNPEDPTTPFRHKPGSVFSVEGENLDLAMSKEEVVAMIGDGPCMVKTLTRHHLYCEPPTEQPLPQHHAFREAPDALPEFTVQMGNLRFSLGRVQYDGESPMAFPVAAQVGLGVGTSLLALAVLIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVYAERVFFPGHQESPLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDILRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGMPVKVLDCDTISQAKEKMLEQLYKGVPLAQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRSGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQAQQHGISDQDTVHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLYARDIPRYKQMVERYYADIRQAIPASDQEMNSILAELSRNFSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKVTDL",
        "proteome": "UP000007646",
        "gene": "PLXNB1",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0017154",
                "name": "semaphorin receptor activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0071526",
                "name": "semaphorin-plexin signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "0026d234d6c2b29aea981db5e1c859236d744b14",
        "counters": {
            "domain_architectures": 1228,
            "entries": 40,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 4,
                "ssf": 4,
                "smart": 3,
                "pfam": 9,
                "cdd": 3,
                "panther": 1,
                "interpro": 15
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 1228
        }
    }
}