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{
    "metadata": {
        "accession": "F8NHN7",
        "id": "F8NHN7_SERL9",
        "source_organism": {
            "taxId": "578457",
            "scientificName": "Serpula lacrymans var. lacrymans (strain S7.9)",
            "fullName": "Serpula lacrymans var. lacrymans (strain S7.9) (Dry rot fungus)"
        },
        "name": "E3 ubiquitin-protein ligase listerin",
        "description": [
            "E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Mediates ubiquitination of proteins derived from mRNAs lacking stop codons (non-stop proteins) and other translation arrest products induced by poly-lysine sequences and tandem rare codons. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product. May indirectly play a role in chromatin function and transcription",
            "E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation"
        ],
        "length": 1767,
        "sequence": "MVKGQKSSASSGTRKKNARKAAGGPQTPEPIPKEKKPKAKGKGQKKEPKKKVYIPPVKPAPIQPDPLDTMGLVHQLPPELVVALRALGKKDPVTKAKAIEELQSKWVDELKREGDDSPLSFVLVTMLPVWLHRVPVLFTHPARRIRLLAASLHASLLRIQPVREATVGFIQESATIEHVESLLGTWCMSSYDIDRQVASFGQKSWSYTFSSQRENDRVVIDMDKLQTITSFIQKALLDPNGIYLYLNPVPPVAAPPAKKPGSRPMPASKSDNVEHNRSRAEGEEESEMDRNARLRVSAFGAFRWMLDSRAAISADSLGELTEFLCNPALWSSLCPAQHCPYVDMESFGFGQPLVRQNAWVLLSLLMQRWKGSLEHMLPILSTAVLRSAWIDTDVTVRNTMSRPLLLFLKEFPKSWVLDSAFNSPKHDADSDSEDSDTEEEKEADPVLPRGVGNSGSSLAYNEFLQFLELGCSGSPTEGYPIVIIILSTIPSSILSASRSSPLGDFFSSFWAALDGRALSSTERKAPSTAFLSSLLESMVFLLRRVLGGSQGHTVLLSSTGPQESSIQPTEAAKSVIKEQFVRLWDELAAQRLRVGEADAGKLMAQTLVTLNNMDSGLFNEAWEAIVGGVNDKYSVSVSLISSILKVFADQFVEETAPAIATLKLIGKVVEMSVSQCEKALDSEDAELSTHISSLIILIDTFGISLFQRHEFSLRMDDMIICHALKVLQTSYKLILAYLSYRDDPERCSELWHSILYGLSGNPHVILSSLPPLLDASRKGILAEYLQPEEDELDGVVERIFTQVLDGATQSREVTLIRQLLHTPEHFLSKNGFHNLSQTLVHSFTSRLVQALSDPLPELSLHLELIAGVLDTHPSVISPDTILPSVFLAAYLFPISFKQDVSSTATARTIWTSWVTHAPENQRSTISNLIKEKLRDLLTECSMQPKPEHIIQLVTEGCPGIQFDVLADVFPSSEELDSMLSDLPSEPAEPSLALFESLIPPAMEFEDGRLSGATYDRKGYSPYVRVVSTLLHVLIDSRQLSRDNLWALRHILALSDFVNDFLRVPSVPSGLLHSTALTSELTVMITKAHQLTTYLLTSLTEDALHTKVITALSDRSKTVDGLPKLIVDLVNHAAAEDTIRDSRILSSVLQHIFANATKGDADSWMVLARKFEKTAPQTSLSIMSSITRFAPEPSRLDRYRNELAANMLGISGNKVSTEGLLTLRKLVAVAPDPDSEVVFLPQQRAVNVMKACQEWITSDEEVNEEVESMMTLLFYHLAPILQNVPGSHWELVFDVIENNLEHCSISDNTTLVTLGRSLQLIIIIQDLVTTNKALRAEWEERQLSILTLVKNIVTSRLDDAGISAARSLCRELALSVIQDDPKSLVDTNTLAEMCHLLSDPSTVVQKTAYTLLHEAARKKTEYYVIEAAVDTEDAVTAELPMELLVLLQRTLQLGDDFTQENPDDSPESLHTHHQEILGYLLSWMVAFDLFIDASMKVRSSYFNHMRSLDIISTHFIPNIFDILDIFGGNKKAFKLDVWTTDEYYLDMYEPDSALSARLLAAHLYYRALVTVPALIRSWVSDCTDKQLLARVIAYTSSYFSPVIIKAELAQVRDSEASTELAATENLAVKVAPAASEVTASYTVDEHALELTLRMPSDWPLHRMEIRDTKPVGVSEDRWRGWVLGVQQIVWQQNGRVVDGLTLFTKNVTLHFAGQVECAICYSIISMMDGGLPQKPCKTCKNRFHAGCLYKWFKSSHSSSCPLCRSDIL",
        "proteome": null,
        "gene": "SERLADRAFT_445033",
        "go_terms": [
            {
                "identifier": "GO:0061630",
                "name": "ubiquitin protein ligase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:1990116",
                "name": "ribosome-associated ubiquitin-dependent protein catabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:1990112",
                "name": "RQC complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "fc602df98a1e39ab9b1cba929bedc1c50dbb6591",
        "counters": {
            "domain_architectures": 1341,
            "entries": 19,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 4,
                "ssf": 2,
                "cathgene3d": 1,
                "smart": 1,
                "cdd": 1,
                "profile": 1,
                "panther": 1,
                "interpro": 8
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 1341
        }
    }
}