General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "F7D5E1",
        "id": "F7D5E1_ORNAN",
        "source_organism": {
            "taxId": "9258",
            "scientificName": "Ornithorhynchus anatinus",
            "fullName": "Ornithorhynchus anatinus (Duckbill platypus)"
        },
        "name": "Thromboxane-A synthase",
        "description": [
            "Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Also cleaves PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE"
        ],
        "length": 479,
        "sequence": "IYGIWPYSIFKKLGIPGPRPLPFVGTFLEYRNGIFEFDKKCYEKYGKVWGIFDGRQPILAILDPDIIKTVLVKEFHDSFPNRRNFGLNGGLDSSLTIAEYHTWKRIRTIVSPTFTSGKLKEMFPIIKHYGKLLVQNIDKKVKKNEPVNMKRIFGSYSLDVVTSTSFGVDIDSMNNPNDPFVKQITKLLSFTFLSPLFLLTVVFPFLMPVFKKMNLSLFPRDTVEFFVGVTRNFKEKRQKGVHTGRVDFLQLMVDSQSSDSNPEPKMTDMEISTQAIIFIFAGFETTSSTLNFVSYNLATHPEVQKKLQEEIDSILPNKASPTYESIFQMDYLDMVVLETLRLFPPGGRIQRVCKETTQIKGLTIPKGTVVIIPTFVLHRDSEHWPEPEKFLPERFSKEEKASHNPYVFLPFGAGPRNCIGMRFALLNMKAALIHLLQNFSVEPCKETPIPLELDSTGFMKPKKPIILKLVPRSGVDSED",
        "proteome": "UP000002279",
        "gene": "LOC100089880",
        "go_terms": [
            {
                "identifier": "GO:0004497",
                "name": "monooxygenase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005506",
                "name": "iron ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016705",
                "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0020037",
                "name": "heme binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "a02e61ba6c64bb9a9c779746e03a6c43264a16fb",
        "counters": {
            "domain_architectures": 520850,
            "entries": 12,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 0,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 1,
                "ssf": 1,
                "pfam": 1,
                "panther": 1,
                "prosite": 1,
                "prints": 2,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 520850
        }
    }
}