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{
    "metadata": {
        "accession": "F6X4A5",
        "id": "F6X4A5_XENTR",
        "source_organism": {
            "taxId": "8364",
            "scientificName": "Xenopus tropicalis",
            "fullName": "Xenopus tropicalis (Western clawed frog)"
        },
        "name": "Histone deacetylase",
        "description": [
            "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events"
        ],
        "length": 1040,
        "sequence": "MSLPTQSDGVKGREPALEILSRAQGHALPAAVEVSPLLSAAVPTPSSLSPTSGELRAEPRSGSGSGGILDPVGREQQLQQQLLLLKQQQQLQKQLLFAEFQKQHENLTRQHEVQLQKHLKQQQEIMAAKRQQELEQQRKRERQRQEEAEKQRLEQQLLILRNKEKSKESAIASTEVKLKLQEFLLSKSKEVPGNVNHSILQHPKCWGTHHTSLDHSSPPQSGSPATPPSYKVSLLATCDGRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISAFKKRAIEIQVSSVCNSAPGSGPSSPNSSNSAICENGLTGSVPNIASEMLPQQRVLALEGAGGPLGLYTSPSLPNICLQGSTSSLTGQFSPQEGAERQSLRPGGPFINTSPLPALDGGEISTLTAPSLLQHVLLLEQARQQSALITVPLHGQSPLVGGDRVSGSLRSVTKGTRHRPLSRTQSSPLPQSPQALQQLVLQHQHYLDQQHLNKASEAIRQPPTHPEETEEELTEQDGGERCRAIFTLDGGTESEETQEEDGGEEDDEDREDSRTNGVEHALKKLFPDALPLYQGSLPHTALSRTQSSPAAPLSTCSLEPHHRVISTTGLVYDTLMLKHQCTCGDTNNHPEHAGRIQSVWSRLQETGLLGKCQRVRGRKATLDEIQTVHTEHHTLLYGTSPQSRHKLESKNILGTLSQKLYAVLPCGGIGVDSDTVWNELHSPPAVRTAVGSLIELVYKVAAGELKNGFAVIRPPGHHAEESVAMGFCFFNSVAIAAKLLRQKMNVGRILIVDWDIHHGNGTQQAFYNDPNILYISLHRYDDGNFFPGSGSSDEVGAGHGTGFNVNIAWTGGVDPPVGDAEYLAAFRMVVMPVAKEFSPDFVLVSAGFDAVEGHQSPLGGYSVTAKCFGHLTKQLMTLAGGQVVLALEGGHDLTAICDASEACVSALLGMEPTPFDNSVLQQRPSDNAIATLERVINIHGKHWSCLKSSTLGFSILEAQRVELEEAEAVSALASLSVDTDQCNSDSNPRPLEEPMEDEPVA",
        "proteome": "UP000008143",
        "gene": "hdac5",
        "go_terms": [
            {
                "identifier": "GO:0004407",
                "name": "histone deacetylase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000122",
                "name": "negative regulation of transcription by RNA polymerase II",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "d6c3d64972e4f96fa8ee7f36c5ab9c3d77ff021e",
        "counters": {
            "domain_architectures": 4254,
            "entries": 15,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "cdd": 1,
                "ssf": 1,
                "pfam": 2,
                "pirsf": 1,
                "panther": 1,
                "prints": 1,
                "interpro": 6
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 4254
        }
    }
}