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{
    "metadata": {
        "accession": "F2TKX5",
        "id": "F2TKX5_AJEDA",
        "source_organism": {
            "taxId": "653446",
            "scientificName": "Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68)",
            "fullName": "Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68)"
        },
        "name": "DNA replication ATP-dependent helicase/nuclease",
        "description": [
            "Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA"
        ],
        "length": 1684,
        "sequence": "MPSDAFVISSKSRIKLNTFRYAPAVPQYSHNMPTVDQNCDDSGSMDKENAEMKARMGEGDIPVPTPQSSGTKCREVQPEKKSPQTPAHRIPLADLISNTEDAFSRAPGRVISPEDHVFWKHEPCNTDPRDASGSPITRGQKRYRSASPTSSPLGADSKHIMSSPQPLPKFVRTPQHDIAADLWSKYIGKSTGNPGGDAPKPQFAHLVSSSPRTPTAARAGRDLSTLRRSNSCNVYWPTSNTKRRRVDNEQQAVKRVRDIFAGSRSSLLGDGTSKSSKISLLVGKIQETLLKSPRGEISGPSSSTPLPERPDNIAEFSGSPPKPRNENENNPIDTPSKCSRRVMANDAVYNDTMYTIQDLNATLSEFDDDGLDDDFLEFAGKADNQHKPIYSEVGPLPDAVQEERLTGVLYTAHAKPDRPRTGSINKNDKQPTLPTSHAHTNSEEVDEFNDSDDEFPEAMEEVLARYDLKEQTNAGKKPNAILAEPPAPSFGIAAVRKTEPKTPSLDGAISSSGDEFDEDIDLESIEAAMQKVAGINGSSHNRKSRQTIERHLIIDSAENTYLNSKGQSKPQKVLFVQEEKTNNNRTITLRESWYDTPCSKGSYIHLIGSFDHMGRCVVDNSDNMIILHPDHLISATVVADSFTCPRRAVLQDRVKATSEANKPQVYGHILHEIFQAAASANRWDQSWLREIISRTLEHYVESLYEIQVEVSEATEYLMSKIPALSSWADIFMRSRPTIESITEDRSGTTSCLSINKLLEVEEHIWSPMYGLKGNVDATVQVAVQEGTEKKTLTVPFELKTGRNNSNEAHRAQTALYTLLVSDRYDIDVTFGILFYLEATKTFRVRAIRSEIRQMIQQRNRLAEFICKKSDLPPMLKKARICNQCYAKDACFIYHKVMDDGDDESSGMGTSFIEIVGHLTPSHQNFFKKWDALLTMEERDILKFRRELWTMLSNEREGVGRCFGNVMVEPGSAYEETGVPKINRFRYTFFKHQPPSNFSFGDSQLSVGEPIVVSDEKGHFALANGYVTHISRTRISVAVDRRLHNARTRCSNFDADRHQSFTGVMEIVETGGSESTVFPEKAEDTTLYRLDKDEFSNGMATVRNNLVCMMDRNTFQARRLRDLIIDGHIPLFKPTSSSAIPCLPETELNIDQEQAIKKVMSANDYALILGMPGTGKTTTIAHIIRALISQGKSVLLTSYTHTAVDNILLKVKDDNIRTLRLGATTKIHPDVQKFADLAATPKKTIEELRDIYENSRIVATTCLGINHPIFNSRTFDYCIVDEASQITLPVCLGPIRMAKTFILVGDHYQLPPLVQDKEARESGLDVSLFKLLCDLQPASVVNLEHQYRMCEDIMLLSNTLIYSGHLKCGTPEVAQSYLKIPNLGRLKQHHVDSLSLPPNVRNSCLGSRYGRCWIRDLLDPVARTRLVNTDPLEPQATESSKGSRIINPIEATICAQLVESFISVGIPAGDIGVVTLYRSQLSLLKQNLRHHPDLEMHTADRFQGRDKEIIIMSCVRSNSERNVGELLRDWRRVNVAFTRARTKLLIVGSKNTLRDGNELLGNFVQLMDAKAWTYDLPRTAVEQHVFENAENGLTQLSPRKGMEVMRSNSLSPKKRSPTKKIPKKRVTFHDQSPLKDKQRIALSPVKNRQPSAGQRRPEKIGGKLLDGARIVATRPVLMDVLNDLM",
        "proteome": null,
        "gene": "BDDG_06833",
        "go_terms": [
            {
                "identifier": "GO:0004386",
                "name": "helicase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0017116",
                "name": "single-stranded DNA helicase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "c5e6e240671c7047160f5debbd2448c8b8927add",
        "counters": {
            "domain_architectures": 463,
            "entries": 22,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cdd": 3,
                "cathgene3d": 2,
                "pfam": 5,
                "ssf": 1,
                "panther": 1,
                "interpro": 10
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 463
        }
    }
}