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InterPro-Version: 108.0
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{
"metadata": {
"accession": "E8AEM1",
"id": "E8AEM1_SALMO",
"source_organism": {
"taxId": "858315",
"scientificName": "Salmonella enterica subsp. enterica serovar Montevideo str. 413180",
"fullName": "Salmonella enterica subsp. enterica serovar Montevideo str. 413180"
},
"name": "S-(hydroxymethyl)glutathione dehydrogenase",
"description": [
"Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent. In addition, hemithiolacetals other than those formed from GSH, including omega-thiol fatty acids, also are substrates. Also acts as a S-nitroso-glutathione reductase by catalyzing the NADH-dependent reduction of S-nitrosoglutathione"
],
"length": 372,
"sequence": "MKSRAAVAFGPGQPLKIVEIDVAPPKKGEVLVKITHTGVCHTDAFTLSGDDPEGVFPAVLGHEGGGVVVEVGEGVTSLKPGDHVIPLYTAECGECKFCKSGKTNLCQAVRATQGKGLMPDGTTRFSYNGEPVYHYMGTSTFSEYTVCAEISLAKVNPQAPLDKVCLLGCGVTTGIGAVHNTAKVKAGDTVAVFGLGGIGLAVIQGAVQAKAGRILAVDTNPEKFTLAGEMGATDFINPNDYDKPIQDVIVELTDGGVDFSFECIGNVNVMRAALECCHKGWGESIIIGVAGAGQEIKTRPFQLVTGRVWRGSAFGGVKGRTQLPGMVEDAMNGKIRLDPFITHRLPLEQINDAFELMHQGKSIRTVIHFSDN",
"proteome": null,
"gene": null,
"go_terms": [
{
"identifier": "GO:0008270",
"name": "zinc ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0051903",
"name": "S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0046294",
"name": "formaldehyde catabolic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016491",
"name": "oxidoreductase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "6e6b076d581cf5733167d9dad5b9a31c66e6d8d3",
"counters": {
"domain_architectures": 323634,
"entries": 18,
"isoforms": 0,
"proteomes": 0,
"sets": 3,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 2,
"cdd": 1,
"cathgene3d": 2,
"smart": 1,
"pfam": 2,
"panther": 1,
"ncbifam": 1,
"prosite": 1,
"interpro": 7
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 323634
}
}
}