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InterPro-Version: 108.0
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{
"metadata": {
"accession": "D9ZNM3",
"id": "D9ZNM3_9MONO",
"source_organism": {
"taxId": "2560313",
"scientificName": "avian paramyxovirus 2",
"fullName": "avian paramyxovirus 2"
},
"name": "Hemagglutinin-neuraminidase",
"description": [
"Mediates the viral entry into the host cell together with fusion/F protein. Attaches the virus to sialic acid-containing cell receptors and thereby initiates infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion",
"Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins"
],
"length": 582,
"sequence": "MDARSRENLTELGQGGRRTWLMLFRVLTLALTLACLAINIATIAKLDSIDTGRLQTWTTAESDRVIGSLTDTLKVPINQVNDMFRIVALDLPLQMTTHQKEIASQVGFLAESINSVLSKNGSAGLVLINDPEYAGGIGVSLFQGDSASSLDFEEPHLIEHPSFIPGPTTAKGCIRIPTFHMSASHWCYSHNIIASGCQDAGHSSMYISLGVLKATQAGSPSFLTTASQLVDDKLNRKSCSIISTTYGCDILCSLVVENEDADYRSDPPTDMILGRLFFNGTYSERKLNTGTIFQLFSANYPAVGSGLVLGDEIAFPVYGGVRQNTWLFNQLKDHGYFAHNDVYKCNKSDTHQTVLNAYRPPKISGRLWSQVVLICPLGLFINTDCRIKVFNTSTVMMGAEARLIQVGSDIYLYQRSSSWWVVGLTYKLDFQELSSKTGNVINKVSPIAHAKFPRPSFSRDACARPNICPAVCVSGVYQDIWPISTAQNLSQVVWVGQYLEAFYARKDPWIGIATQYNWKKNVRLFNTNTEVGYSTTTCFRNTKRDKAFCVIISEYADGVFGSYRVVPQLIEVETTSKKRLFS",
"proteome": null,
"gene": "HN",
"go_terms": [
{
"identifier": "GO:0046789",
"name": "host cell surface receptor binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0019058",
"name": "viral life cycle",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0019031",
"name": "viral envelope",
"category": {
"code": "C",
"name": "cellular_component"
}
},
{
"identifier": "GO:0004308",
"name": "exo-alpha-sialidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": false,
"in_bfvd": false,
"ida_accession": "8197603f8ca878a7579253a7aaec728ad8f38af2",
"counters": {
"domain_architectures": 7843,
"entries": 8,
"isoforms": 0,
"proteomes": 0,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"pfam": 1,
"cathgene3d": 1,
"ssf": 1,
"cdd": 1,
"pirsf": 1,
"interpro": 3
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 7843
}
}
}