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{
    "metadata": {
        "accession": "B5BNZ8",
        "id": "B5BNZ8_BBTV",
        "source_organism": {
            "taxId": "12585",
            "scientificName": "Banana bunchy top virus",
            "fullName": "Banana bunchy top virus (BBTV)"
        },
        "name": "Master replication protein",
        "description": [
            "Essential for the replication of all genomic viral ssDNA (trans-replication). The closed circular ssDNA genome is first converted to a superhelical dsDNA. Rep binds a specific hairpin at the genome origin of replication. Introduces an endonucleolytic nick within the conserved sequence 5'-A[GT]TATTAC-3' in the intergenic region of the genome, thereby initiating the rolling circle replication (RCR). Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester. The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase. The polymerase synthesizes the (+) strand DNA by rolling circle mechanism. After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication. Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities"
        ],
        "length": 286,
        "sequence": "MARYVVCWMFTINNPTTLPVMRDEIKYMVYQVERGQEGTRHVQGYVEMKRRSSLKQMRGFFPGAHLEKRKGSQEEARSYCMKEDTRIEGPFEFGAFKLSCNDNLFDVIQDMRETHKRPLEYLYDCPNTFDRSKDTLYRVQAEMNKTKAMNSWRTSFSTWTSEVENIMAQPCHRRIIWVYGPNGGEGKTTYAKHLMKTRNAFYSPGGKSLDICRLYNYEDIVIFDIPRCKEDYLNYGLLEEFKNGIIQSGKYEPVLKIVEYVEVIVMANFLPKEGIFSEDRIKLVSC",
        "proteome": null,
        "gene": "master-Rep",
        "go_terms": [
            {
                "identifier": "GO:0006260",
                "name": "DNA replication",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0003723",
                "name": "RNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003724",
                "name": "RNA helicase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "cb80c3b031ca2fd79bbbd2adcc26ed7bfeea18ca",
        "counters": {
            "domain_architectures": 4697,
            "entries": 7,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 1,
                "cathgene3d": 1,
                "cdd": 1,
                "pfam": 2,
                "interpro": 2
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 4697
        }
    }
}