General Handler

HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept

{
    "metadata": {
        "accession": "B4LRB3",
        "id": "B4LRB3_DROVI",
        "source_organism": {
            "taxId": "7244",
            "scientificName": "Drosophila virilis",
            "fullName": "Drosophila virilis (Fruit fly)"
        },
        "name": "Fatty acid synthase",
        "description": [
            "Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain"
        ],
        "length": 2419,
        "sequence": "MGSKKKEELLKTQNNEAVGEELEIVISGISGKFPESSNIEEFKHNLLNGIDMVTDDPRRWEAGIYGLPERMAKMRDEDLEKFDDKFFSVHQKQAELMDPCMRMLLELTHEAIIDAGINPSELRGTRTGVYIGLSFVETEHEIPNMEPSSINGYCLTGCARAMFANRISYTFDFKGPSFIVDTACSSSLVALSHAYTDMRSGRCDYALVAGVNLILKPIFALQFLRLGIVSQDGSCKTFDAGANGYARADTCAVVFLQRRAQAKRLYASILNVRTNTDGFKEQGVTFPDGRMQQQLLHETYSEIGLNPDKVVYVEAHGSGTPVGDDQEANMLSNFFCHPSRPAPLLIGSVKSNMGHAEPASGVSALAKVIIAMEEGIIPRNLHYHNPNPAVPALVEGRLKVMDRNLPWQGGIVGLNSFGFGGANAHVILKSHEKQKKPSPKAHKTPLKLVICSGRTEQAVHQLLDAATKHRNDDEFLALMNDIHLKPIPMHPYRGFSLLGSAGPVKQEICIYEEEKRPIWFVYAGMGSQWASMAKDLMQIEVFNKSIQYCAEVLTQMDFDLIEVLTHSTESTFDNMLNSFVSIAAVQVALTDLLKTLDIKADGIIGHSAGELGAAYMDGCLTAEQTVLAAYWRGKSILETPGLPQGKMAAVGLSWNEIGNHLPPDCYPVCHNSDNNCTVSGPVASMDATIQKLNGSGVFVRAVESGGYAFHSRYIANAAPILRKNLERLITDPKLRTNRWLSTSVPERDWQTPACRMASATYFINNLISPVLFHEAICHIPKNALVVEIAPHGLFRSILRALGPKISYVSLMQRGHPNNSEYLLSQIGQLYVAGGQPQLLGLSLSQTISYPVSRGTPMLSSLIGWDHTQKWSYPKFQGGRQTSQLSVELDLSKEEYAFLAGHKIDGRILYPATGYLTLAWIMLAQQKGCDFQRTPVVFEDVVFHRATILGQDVGSAVKLAVNYFQGSGNFEICEGSSLVASGKIRLVANVQELQLNLPGLPGSAGLAKLCTKDVYKELRLRGYDYGGIFQGIIDVDNLGVAGRLAWADNWISFMDTMLQFRILSNSMRELYVPTGIERVVIDPVKHLELAKQQQQKLPVSYHRNISVVKCGGVEVHKMKTAQTQRRSGGQSPPVLERYSFTPHMQHLDPRGDQHRSKHIALTVAMQLIIENSGGALKIKGVELAGTRTEGLNAVKLLELIEREPILVGDVAVATNSNSNESVLNALLLDSGVRVIVADPAKAAVECQCDFVHAVDLLATECTARDLQLQHCIDTVKAETGFLLLEESLSAYRSTGQALLQRLNLLPVMEQVYDTDRTLILARKLAVKDFTSSLVIRISNNHFKWVTDLKAALLKSQSEGSNVYLVAQGEPRTGALGFINCLKREQIDYRIRLYLLQDPELPEFSLTSTSFADQIAKDLSINVYRNGNWGSFRHLPLNTHQPLLTVEQAYVNTLIKGDLSSLKWIESPRNTNVNLNKWEPCTVYFAPLNFRDVMLASGKLSQDALPADLAHQDCVLGLEFAGRDSTGRRVMAMVPAKSLATNCLANKNLLWDIPDNWTMEEASTVPCVYATVYYALVVRGQMKKGERILIHAGSGGVGQAAISVALHHGLTVFTTVGSKEKREFLLKRFPKLLARNIGNSRDTSFEQMILGETNGEGVDLILNSLSEEKLQASVRCLGLNGRFLEIGKFDLSNNNPLGMSVFLKNTSFHGILLDSVMEGEEEMQRHVVSLVTEGIRNGAVLPLPTTVYTDQEIEKAFRFMASGKHIGKVVIKVRNEEQQSALPKPRLTNAIPRTYMHPEKSYIIVGGLGGFGLELANWLATRGARYIVLNSHSGLKTGYQSLMIRRLHERGVQVIVDINDVTSAMGCIKMLESSNNLALVGGIFNLAAILKDAIFEEQTVKNFELVTAPKILTTMHLDQCSRRMCPALEHFICFSSLASGRGNPGQTNYGLANSAMERICELRQADGYPGIAIQWGAIGDTGLIIEHMGNNDTVIGGTLPQRMSSCLQTLDIFMQQPHPVLASMVLAEKRKPEQSSRQSLIATIANIMGLRDVNSIQDKTTLFDLGMDSLMSTEIKQTLERNFDLVLSAQEIRQLTFSALKNIDTREAQVTASRSDSVIEPTSVNGANIMGRTTIAQTDETRQVFAKEVLPQDVLVRLHSKATIASKEPAAFFLAPIEGFTIAVEALAASLTCPAYGLQCTEQVPLDSIEACAAYYLQQIQKLQPHGPYNIVGYSYGCLLAHAIGVALEQRRFSVKVIMLDGAPTMASGYVQEAKKQTDDLNRQQSMTLAYFGALLADVDYNQLLRILEGVKTWNLKLNKLADTLASHTQQTKDVIKKAACMFQQKLLLSESYKGAKQLNSDVVLIKSAEHNAIMTQDDYGLREICSAPIDMHVVAGTHRTFLKEAQTLKIMERVLHKHSC",
        "proteome": "UP000008792",
        "gene": "Dvir\\GJ21725",
        "go_terms": [
            {
                "identifier": "GO:0016746",
                "name": "acyltransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016740",
                "name": "transferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016491",
                "name": "oxidoreductase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0031177",
                "name": "phosphopantetheine binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0009058",
                "name": "biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004315",
                "name": "3-oxoacyl-[acyl-carrier-protein] synthase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006633",
                "name": "fatty acid biosynthetic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "7109102a742512c5825e82570e51543cc56db086",
        "counters": {
            "domain_architectures": 870,
            "entries": 65,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 9,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 3,
                "pfam": 10,
                "cdd": 3,
                "ssf": 7,
                "cathgene3d": 8,
                "smart": 6,
                "panther": 1,
                "prosite": 1,
                "interpro": 26
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 870
        }
    }
}