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{
    "metadata": {
        "accession": "A1CPR3",
        "id": "A1CPR3_ASPCL",
        "source_organism": {
            "taxId": "344612",
            "scientificName": "Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)",
            "fullName": "Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)"
        },
        "name": "DSC E3 ubiquitin ligase complex subunit A",
        "description": [
            "Catalytic component of the DSC E3 ubiquitin ligase complex which is required for the srbA transcriptional activator proteolytic cleavage to release the soluble transcription factor from the membrane in low oxygen or sterol conditions. Required for growth during hypoxia and triazole drug susceptibility, as well as for virulence in a murine model of invasive pulmonary aspergillosis (IPA)"
        ],
        "length": 802,
        "sequence": "MDNRGSFFFFLIVFYLLLSSQSRPPLIDQDREHQREVARERDALRLLNETNYGDFDPQADKWLPFTGVRKNDSYAWDILPHAQDRARHQLRNAILDAGLEPPKVLEDPEASPPLNFTQLLLPVYRNVTGKLRGEWVRRKQDGEHPKLNTTAIALENEYFTHEFSLNITGSSGTFYLDLREGGGEELRVDDGHVREIRATLAVESDDLWENTWYLSLFGVHFPESGGIILTSTSEKYGGLFALPHLTLSPDAYELSHRLLMKSLSDTLSEKANRPPTLFPWPSLVGSEQVEFPAPKCEHVVYIQQHPVSIHGSLADKPLIDQIEQELRYPIGAPIPSAPLMVMSAVVFSPDCGYILETKGTPDFPPSEALYLSGPKIEEFGKYSARLVFLVCGVFAAQITLLLRQIKEASTPSTRSRISFYTIALMAIGDAFVLVFILLELYPSVSFLVMTTASFLTFLSVSYIGMKFMMEIWAVQAPERREQERRSNPTPNQRTGGLPLPATMARDTGATPIIVTPDQDPPAEENDLPTNRGTAPTAQETRNDVGAMYARFYFTLFVMLIISIWSFLWPNRLGALYARALAFVYLSFWVPQIGRNVMRNCRKALRWDFVVGQSLLRLFPFIYFLTVRGNVLFVRPDTTTAMALAGWIWAQVWILASQDILGPRFFVPRGWAPPAYDYHPVLRDSTDPEADLESGGVLPIGALRADERDISTDSKDGEDKPRSKDRKKAVFDCAICMQEIEVPVLAALGAAGGSSVTDGATSILSRRTYMITPCRHIFHSTCLESWMRLRLQCPICRESIPPV",
        "proteome": "UP000006701",
        "gene": "ACLA_023480",
        "go_terms": null,
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "5381c30d31b9b818c4e3b50b5a6304c89886dea9",
        "counters": {
            "domain_architectures": 486,
            "entries": 11,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 2,
                "cathgene3d": 1,
                "ssf": 1,
                "smart": 1,
                "profile": 1,
                "panther": 1,
                "interpro": 4
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 486
        }
    }
}