GET /api/protein/UniProt/A0AAV6SZ46/?format=api
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Content-Type: application/json
InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0AAV6SZ46",
"id": "A0AAV6SZ46_SOLSE",
"source_organism": {
"taxId": "28829",
"scientificName": "Solea senegalensis",
"fullName": "Solea senegalensis (Senegalese sole)"
},
"name": "Protein phosphatase 1 regulatory subunit 19",
"description": [
"Plays a central role in maintaining S6K1 signaling and BAD phosphorylation under normal growth conditions thereby protecting cells from potential deleterious effects of sustained S6K1 signaling. The URI1-PPP1CC complex acts as a central component of a negative feedback mechanism that counteracts excessive S6K1 survival signaling to BAD in response to growth factors. Mediates inhibition of PPP1CC phosphatase activity in mitochondria. Coordinates the regulation of nutrient-sensitive gene expression availability in a mTOR-dependent manner. Seems to be a scaffolding protein able to assemble a prefoldin-like complex that contains PFDs and proteins with roles in transcription and ubiquitination"
],
"length": 482,
"sequence": "MMCPKKTQVVKDCESRILHWKKVSGDYEALNDRLKTLPDQLSYDIMVPFGSLAFMPGKLVHTNELTVLLGDNWFARCSAKQAQKLVDHRMKHVKHELDDLSKTMKNFEARVGLVKDLETISANKGDCVDIREEVRNNGTSVTKGRQRIAHRPNSKPKLDAVLDLKEEDEENDGEDGSDEGSGKGILTEEELWARLDELEKLEELEDDQDRLSDNADMNGEDTSSSSSEEEKERDAAHPVNGVSLKPSWTSVPHSIAPPVMDRKQEEEEDEEEEGNCLPTIFFSHTVEPKKVRINTGKNTTLKFSERKEQKEHSKRKKKNGHNGHSHHELHKITTPADIYRLFVDVKNGEPIPRKSILKSRSRENSVCSDTSESSAADFEERRVIGRSFSYDEATHSDTSDGNADEDSPVAVPLRATSRFEAFSGTVIEKDPMPSAVPHLTITPPALPTILERKQEEVASDFAPPQEAPKKVSKFKAARLQQK",
"proteome": "UP000693946",
"gene": "JOB18_020507",
"go_terms": null,
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "bc0bdc5e1accc6ba61a70135255c8cbcb5257e7e",
"counters": {
"domain_architectures": 14091,
"entries": 5,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cdd": 1,
"panther": 1,
"pfam": 1,
"interpro": 2
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 14091
}
}
}