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{
    "metadata": {
        "accession": "A0AAN6UW88",
        "id": "A0AAN6UW88_9PEZI",
        "source_organism": {
            "taxId": "1934379",
            "scientificName": "Dichotomopilus funicola",
            "fullName": "Dichotomopilus funicola"
        },
        "name": "Serine/threonine-protein kinase MEC1",
        "description": [
            "Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability"
        ],
        "length": 3073,
        "sequence": "MLDAFEIIDTSGVVLWSRNYTAVSPSVVNNFISDVFIEEKSTVAGAKDGASAASNPPYKHEQHSLRWTFNKELGIIFVAVYRSLLHLPWIDKLVDNIKAIFVSLYGDQLRKPNTTIVECVKFDEYFDQQLGELEQSGSRSNVLAYSDEKNPADIGDDPPLPPSLVLPTKSQAKSSAESTPVVTPDPSRPSTPSAGHLLVAKPGPGGKLSRRARKMQNNNSAPVSSGDEGPGRRGKPTKAAKRGRKWDADGLADETDDVQLDYSVPTLTSDSEADAGGRPGAVEEVDSATWGARTKGKFVLRDLGDEVNSILADAEAKKRAAATTTEGSSGLVGSSLSAIGGLFRNVVGGKTLTKQDLEKAMKGMEEHLLKKNVAREAAVRLCEGVEKELLGVKTGNFESINSRIQVAMEASLTKMLTPTSSLDLLREIDSITAPPATSLRKARPYVMSIVGVNGVGKSTNLSKICFFLLQNKYKVLIAAGDTFRSGAVEQLAVHVRNLKELTTREGGQVELYQKGYGKDAAAVAKDAVSFASQEGFDVVLIDTAGRRHNDQRLMSSLEKFAKFAQPDKILMVGEALVGTDSVAQARNFNAAFGSGRSLDGFIISKCDTVGDMVGTLVSIVHATNVPVLFVGVGQHYSDLRNFSVKWAVEKLLRHQSLQPPDNLAGGAQNHANNPPPSTLAAQLVEDISTSTASTTTKSTRPSDETAELKRLFAAIERVKDDPASLRTHNERVEHNHLLVYVCGSVFLEGLKLDDAFADRERLRADALKAVNFLEATIRETPSVLGCVTDGKLFLRRGAEPLWTWIMPKLLRMLGHGRCLEISGEIEKLCRYVLILAAGNAPLWNYGQAVMGYFWANLNAIITHARSKLSSPHTTLADIKLPPQAFFDTLPVNAFPGCTFTLRDSEHALRHALSLLRVIASVLMEKPGSRPFLVYGQHTVSLLDTLQPLCSILVAWPTPVGVGLAPLLQTAIDLAKSQDVSRVPESVLCHKANAALVLVCAELLLDPHLLLADGEDGASLRDTYCVVLVHLAGASIKHAPTSRLVVSGLLPLAQRVVSENPLLGVETDVWLPDPTTFSSNDLRHQIRDLTVCAASNSSGTPPAKRQKLEGDSGVLDELRTQLCLAVDAPQSSSMDELDDPIIGCFPTMDEEDQCRLIDLISRTLCVADHTLTLKGQVSSMPVFECSFCSEMKPANLPVAERLHKIQAFGISVFTKLIKLPSLLASRRPRVVAMIALRRLAKHSADTEFWDLNKSSPGQWCLQSLQSSIRELRIAAGRALPVFLTEPTYQFDWGVLESNRTTSLGLLRTISDKGAANLHETCIMAWAQVGRGVSADELNLVVLKLVEYLGYRNMIVPALAFNEILSLAEFKGETPAQLFHPFWANLAFHVVKDVVSKPQTAQFVADLMQISVPDLLLLLQKHALPWLILSKRRDVIQKITEARGDTETWETCIDAANLPSILVLLLVQDVPDVAAHTMSLLEHVSPHVARFQLVELLRTDPLPIALELLKAAAGADETRRARVREALTMISTLLLPGHKGDQSKKSQIVGSYLQQHVLGLTARLSEVITDSWLSLAPVSEQIRCIGAMEEMIRICKSYACIARPQISACLISALASDSLRAAAFSCWEVMLTHMDEADVEALAETTFFVIGCYWKSFDDTTKKKASGLIDQLLAKHTRILSKYIHRLPSLRHVEELQGTCGLLDQLREPLDTRGSFVLFAERLCHENPGVVEQALIELAAFLDQNQNYLQTSAISEQPDSTIVTLSRSLLDCAAKYNGYHQEISRLCAQAIGLVGCLDSNRLETEREQEQFVVIRNFEDARETTDFVLFVLENVLVKAFLSTTDTKFQGFLSYAMQELLARSDLRSACLCQGQGTGEVIYRKWLAFSESTREVLTPFLSSRFCVAPMAEQTTEYPIFKPGRSYAAWLRALVLDLLRHGQNPFSQAVFEPFNRLIKVKDLVVTEFLLPYLVLHVIVAHSKADFKDKVAAELAAILKYQPPENASYMEREETKLFYQAVFRILDYCMRWLQVKKSQTPVTPKDETWVKEVQKVISKLDPELISQRAIDCNEYARALFFLEPHLGNRQKKAPKQQGSDPILQSLQKIYTQIDDPDGLDGVSTLLQDITLDQQALNDRKAGRWTAAQTWYEIKLAKTPEDVDIQIDLLTCLKESGQHDVLLNCVEGMAVNSNKVAPFAVEASWATGRWQTLEKYLRLHSAGDVSEVFNLGVGQALLCLRDGKVDKFREHVQMLRDKVAGSMTYTATSSLRASHDAMLKCHVLTDLEIIVSHGDHGNKDPHGTLVALDRRLEVLGAYVSDKQYLLGVRRAAMELMRPKFQNGDISLQWLSSARLARKSGSMHQSFNAVLHAQQLGDGSAIIENARLLYKDGHHRQAIQTLQLAISTNSFINDSSISIGVQPTSSKGPDAQRNLLTAQAHLLLAKWLDSTGQTHAGALRSQYQQAAKTYGQWEKGHYYLGRHYKKILESEKALKPDDQTDEYLSGETAKLVIENYLRSLNFGTKYLSQTLPRILTLFCDLGAQVDKAPDGKISLSVELHTRRVDILHGLYKHFYKNLARMPAYIFYTSLSQIVARIAHSNLEVFKVLEQMILKVVESHPQQALWYIFPLMTTRQPGERRSRGMQILQAARSISKKAEGSSDDLRQLLRKGEKLAEQLLLACNNGDFQSNRTTVASITRDLNFNHKCTPCPLVIPNEASLTATLPTLTDNVRKHKAFSRDVITIHAFLDHVLVLGSLAKPRKLTARGTDGKQYGMLIKPKDDLRNDQRLMEFNGLINRSLKRDAEASRRQLSIRTYAVTPLNEECGIIEWVDGLKTLRDILAGLYRTRGVVPNYTELAMQMKQATTGDKNIHIFTENVLGKFPPVLPEWFISQFPNPSAWFAARLKYTRSCAVMSMVGTILGLGDRHGENVLLEESNGGVFHVDFNCLFDKGTTFAQPERVPFRLTHNMQAAMGIYRYEGPFRHCSELTLRILRQQEETLMTILEAFIYDPTLDLQRVKKRSREVVNLNPISVVESIRRKVRGLLPEESIPLGVEGQVEELIKQAVDPRNLAAMYIGWCPFL",
        "proteome": "UP001302676",
        "gene": "C8A04DRAFT_15145",
        "go_terms": [
            {
                "identifier": "GO:0005525",
                "name": "GTP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006614",
                "name": "SRP-dependent cotranslational protein targeting to membrane",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0004674",
                "name": "protein serine/threonine kinase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003924",
                "name": "GTPase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005047",
                "name": "signal recognition particle binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006886",
                "name": "intracellular protein transport",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005785",
                "name": "signal recognition particle receptor complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "aefead8a770d7f1d8ba23286f89f4edba7e56318",
        "counters": {
            "domain_architectures": 16,
            "entries": 53,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 6,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 5,
                "ssf": 5,
                "cdd": 2,
                "smart": 6,
                "pfam": 10,
                "profile": 3,
                "panther": 1,
                "prosite": 1,
                "interpro": 20
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 16
        }
    }
}