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{
"metadata": {
"accession": "A0AA97KCI3",
"id": "A0AA97KCI3_EUBMA",
"source_organism": {
"taxId": "481883",
"scientificName": "Eublepharis macularius",
"fullName": "Eublepharis macularius (Leopard gecko)"
},
"name": "Intraflagellar transport protein 81 homolog",
"description": [
"Component of the intraflagellar transport (IFT) complex B: together with IFT74, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds tubulin via its CH (calponin-homology)-like region. Required for ciliogenesis. Required for proper regulation of SHH signaling. Plays an important role during spermatogenesis by modulating the assembly and elongation of the sperm flagella"
],
"length": 675,
"sequence": "MSDQLKFIVEKLNKEPFKKNFNLITFDSLESMQLLQLLSDVLGEIDPKHVVDIREELPEQTAKRMLSLLGILKYKPPGGTSDLSTFRQGLVTGSKPVIHPVLYWLLQRTNELKKRAYLARFLIKVDVPMEILQDETVADTNRQHEELMEAFKNLHKECEQLKTSGFSTAEIRRDITAMEEEKDQLIKRVERLKKRVETVQNHQRMLETARQLRVEKEREQSLAQQKQEQKIQLFHAEQKLQRVQLQLKDMRHAGVDSKPESLMKRLEEEIKFNTYLVSEKFPREVETKKQLLYLLQKVAAEPAMGQSDLNELETKIHEANAQINQLLEKRMMKYEPIDSKFSMYRQQASIISRKKAAKAEELQAAKEEMSSLERQMLQKSNQAQGMNGMEVLKGDEFKRYVNKLRSKNTVYKKKRLEIAEITAEYGVLQRTEELLQQRHEDIQQQLKAIEDKKGISGYSYTQEELERVSAVKSEMDEVKGRTLDNMSEMVKKLNTLVADKKSSLAPIIKDLRQLRQKCQELTQECEEKKTQYDSCAVGLESNRSALAQEVKSLREECRQEESHYHNTNCMKRILDAQLQRAKEEMKMYVSPDPQDRRKAFREQYSRMITEQESLGKKLREKQKAVRESHGPNMKQVKMWRDLELLMLSKKECFLQRPNQVIGHVVQEVEDRLVVL",
"proteome": "UP001190640",
"gene": "IFT81",
"go_terms": [
{
"identifier": "GO:0015631",
"name": "tubulin binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0042073",
"name": "intraciliary transport",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0060271",
"name": "cilium assembly",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0030992",
"name": "intraciliary transport particle B",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "5d389a2eb1d926fecd72b84be8c42438246dc029",
"counters": {
"domain_architectures": 1967,
"entries": 6,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"pfam": 1,
"panther": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 1967
}
}
}