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{
    "metadata": {
        "accession": "A0AA41N4J9",
        "id": "A0AA41N4J9_SCICA",
        "source_organism": {
            "taxId": "30640",
            "scientificName": "Sciurus carolinensis",
            "fullName": "Sciurus carolinensis (Eastern gray squirrel)"
        },
        "name": "Mitochondrial tRNA methylthiotransferase CDK5RAP1",
        "description": [
            "Methylthiotransferase that catalyzes the conversion of N6-(dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate protein translation by the ribosome. Specifically inhibits CDK5 activation by CDK5R1. Essential for efficient mitochondrial protein synthesis and respiratory chain"
        ],
        "length": 604,
        "sequence": "MRPVQCILRVQRSLRWEWMTSVSWLLLKTCRAHSTLPSTACPSPGQQEDGVRKDFSSRLASGPTFQHFLSASAPQEKSCSPEAEDPPPYLTVDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKTLKTKRPRSRVPLRIGILGCMAERLKEEILNREKMVDLLAGPDAYRDLPRLLAVTESGQQAANVLLSLDETYADVMPVQTSPSATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPVASILEEVRKLSDQGLKEVTLLGQNVNSFRDSSEIQFNNAVSTNLSRGFTANYKAKQGGLRFSHLLDQVSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLDAMRRGYSREAYVQLVHHIRESIPGVSLSSDFITGFCGETEEDHLQTVSLLREVQYNMGFLFAYSMRQKTRAYHRLKDDVPEEVKLRRLEELITVFREEASKANKICVGCTQLVLVEGPSKRSATDLCGRNDGNLKVIFPDAELEDAANPGLKVRAQPGDYVLVKEGQYDWSLTEVVPKLQRQVRLVSRSRLVEERISLCCVDIVYSH",
        "proteome": "UP001166674",
        "gene": "SUZIE_173975",
        "go_terms": [
            {
                "identifier": "GO:0035596",
                "name": "methylthiotransferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0051539",
                "name": "4 iron, 4 sulfur cluster binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0003824",
                "name": "catalytic activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0051536",
                "name": "iron-sulfur cluster binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016740",
                "name": "transferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006400",
                "name": "tRNA modification",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "6c45c6d2798f5e3bef466d8ce7e2d68e5853059e",
        "counters": {
            "domain_architectures": 18732,
            "entries": 27,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 2,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "profile": 2,
                "cathgene3d": 2,
                "ssf": 1,
                "smart": 1,
                "pfam": 2,
                "panther": 1,
                "sfld": 5,
                "hamap": 1,
                "ncbifam": 2,
                "prosite": 1,
                "interpro": 9
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 18732
        }
    }
}