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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A9W2VUU2",
"id": "A0A9W2VUU2_PANPR",
"source_organism": {
"taxId": "9691",
"scientificName": "Panthera pardus",
"fullName": "Panthera pardus (Leopard)"
},
"name": "Amyloid beta precursor like protein 1",
"description": [
"May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I",
"The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis"
],
"length": 631,
"sequence": "MGPTSPAARGLGRHPGPPPLPLLLPLLLLLLRAQLAVGSLAGGSPGAAEAPGSAQVAGLCGHLTLHRDLRTGRWEPDQQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRGGRCAHPHHQVVPFQCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACRSQGLILHGSGMLLPCGTDRFRGVEYVCCPPPVTPDPSGTAVGDPSTRSWPLGGRVEGGEDEEEEESFLQPVDDYFVEPPQAEEEEEEERVPPSSSHSPAGFSKVTTTARPTDGVDVYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQGDPPQAERVLLALRRYLRAEQKERRHTLRHYQHVAAVDPEKAQQMRFQVQTHLQVIEERMNQSLGLLDQNPRLAQELRPQIQELLHSEHLGPNELEAPAPGGSSEDKGGLQPLDSKDDTPVALPKGSAEQDAASSGKEKMSPLEQYERKAPAGTGVSREAVSGLLIMGAGGGSLIVLSLLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP",
"proteome": "UP001165780",
"gene": "APLP1",
"go_terms": [
{
"identifier": "GO:0008201",
"name": "heparin binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0046914",
"name": "transition metal ion binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0016020",
"name": "membrane",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "9de1e266e3e584c01d58ea56cfb911de011004fe",
"counters": {
"domain_architectures": 2045,
"entries": 28,
"isoforms": 0,
"proteomes": 1,
"sets": 0,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 3,
"smart": 1,
"profile": 2,
"ssf": 3,
"pfam": 4,
"panther": 1,
"prints": 1,
"prosite": 2,
"interpro": 11
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 2045
}
}
}