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{
    "metadata": {
        "accession": "A0A974C904",
        "id": "A0A974C904_XENLA",
        "source_organism": {
            "taxId": "8355",
            "scientificName": "Xenopus laevis",
            "fullName": "Xenopus laevis (African clawed frog)"
        },
        "name": "Chromatin-remodeling ATPase INO80",
        "description": [
            "ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair",
            "ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair. The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Involved in DNA replication. Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle"
        ],
        "length": 1539,
        "sequence": "MASDLEATEDGNSTDLAKPLYLQYLERALRLDQFLRQTSAVFNRSISSDESEDELDETPILPEAEDPSLQVKEEPMSPLLGEPSGEGSTDLLPVHALNGVLKPEPKSERGSFYNFSKLKKSRKWLKNILLSDDSSDTDSLSEEDEEELSLSKEELHDMLRLHKYKKLHQSKYQKDKELHQYQYYSAGLLSTHDPFYEQQRHLLGPKRKKIKEEKKFKAKLKKVKRKRRREEDLSEDELPRRHHHTKVFAKFSHDAPTPIGKKKHLTLEQLNARRRKVWQMIVKKELPKAYKQKVSARNLLLTNSKKLAHQCMREVRRAAIQAQKNCKETLPRARRLTKEMSLYWKKYDKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLNFLITQTELYAHFVSRKRESGPDCIQEEILRKLEDSSSQEQVGGSYLNLSQMDYDSDYYKSQALKNAEEAFRIHQAQTRSFDEDAKESRAAALRVAIKSESGFGESYSLANPSIRAGEDIPQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFSRFVPKFKVLPYWGNPHERKVIRKFWGQKTLYTQEAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHDEFSEWFSKDIESHAENKSAIDENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCSLTTRQKLLYQALKNKISIDDLLQSSMGTAQQAQNTTSSLMNLVMQFRKVCNHSELFERQETWSPFHFSLRPYQISKFLFRHGNINCMNWSRNRWLRVLLSPFAPDHIQQSLFHRNGSDQESCFSFLRFIDVSPAEIANLMLRGHLARWLALFLSLKAAYRLHHARVWEERSVSDSRNSYLTNRSLILWVNFALSFPNIHSSSTLQELVFTSHCKPISGCGDYVLHGRKSGQSQVLHCQITQFPSFLYVTAPPVTAPPIDIYCNDRSAEYERREFREGGGPVSRQCLMFGAPELYADWPQRQLKFFPASPGGLKAIRPCNGWSYIKIPDKESLITDSGKLYALDLLLTRLKSHGHRVLIYSQMTRMIDLLEEYMVYRKHTYIRLDGSSKISERRDMVADFQSRTDIFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRVVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRQRQEEKRQQEETNKVKERKRKREKYAEKRKKEDDVDGRRKKEGVNLVIPFLPSADNSNMSADGEDSFISVDSAMPSPFSEISISSELHTGSIAPDESSNDMLVIVDDPSSSAQQSRGTNSPASITGSENLNGVSNQETPNSSRGNTSRNRGRAKVGANGSKGGKSRSRKSTAGSAAAMAGAMAGAAAASAAAYAAYGYSVSKGLPASSPLQTSLLRTSGMSDFGPLNTSSPIKSPLSKRNNPIGLAPETPTRRHSKASNTRGGL",
        "proteome": null,
        "gene": "ino80.L",
        "go_terms": [
            {
                "identifier": "GO:0003677",
                "name": "DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0005524",
                "name": "ATP binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0140658",
                "name": "ATP-dependent chromatin remodeler activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006281",
                "name": "DNA repair",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006338",
                "name": "chromatin remodeling",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006351",
                "name": "DNA-templated transcription",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0031011",
                "name": "Ino80 complex",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "234c2002ae32d97fe4751d9a01209a03103586e6",
        "counters": {
            "domain_architectures": 3606,
            "entries": 23,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 3,
                "profile": 3,
                "cathgene3d": 2,
                "ssf": 1,
                "smart": 2,
                "cdd": 2,
                "panther": 1,
                "interpro": 9
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 3606
        }
    }
}