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{
    "metadata": {
        "accession": "A0A974C8V1",
        "id": "A0A974C8V1_XENLA",
        "source_organism": {
            "taxId": "8355",
            "scientificName": "Xenopus laevis",
            "fullName": "Xenopus laevis (African clawed frog)"
        },
        "name": "E3 ubiquitin-protein ligase",
        "description": [
            "E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates"
        ],
        "length": 2578,
        "sequence": "MADVDPDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRCFETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLDVSAECTRRIVGVEGAIKALCNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHKDTLHSAMAVVSRLCGKMEPQDTSLETCVESLSSLLKHEDHQVSDGALRCFASLADRFTRRGVDPAPLAQHGLTEELLSRMAAAGGTVSGPSSACKTGRGTSGGPSTSGDSKISNQVSTIVSLLSTLCRGSPVVTHDLLRAELLDSMESALQGDERCVLDTMRLVDLLLVLLFEGRKALPKSSAGSTGRIPGLRRLDSSGERSHRQLIDCIRSKDTDALIDAIDTGAFEVNFMDDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRHGANPDLRDEDGKTPLDKARERGHSEVVAILQSPGDWMCPVNKGDEKKKKDSNREEEECNEPKGDPEMAPIYLKRLLPVFAQTFQQTMLPSIRKASLALIRKMIHFCSEALLKEVCHSDAGHNLPTVLVEITATVLDQEDDDDGHLLALQIIRDLVDKGDDLFLDQLARLGVISKVSTLAGPTSDDENEEDSKPEKVRIHLFPLYSAHKGIQAAASQLKEDEPQEDAKELQQGRPYHWRDWSVIRGRDCLYIWSDAAALELSNGSNGWFRFILDGKLATMYSSGSPEGGSDSSESRSEFLEKLQRARSQVKPSTASQPILSTPGPGKLTVGNWSLTCLKDGEIAIHNSDGQQATILKEDLPGFVFESNRGTKHSFTAETSLGSEFVTGWTGKRGRKLKSKLEKTKQKVRTMARDLYDDHFKAVESMPRGVVVTLRNIATQLESAWELHTNRQCIEGENTWRDLMKTALENLIVLLKDENTISPYEMCSSGLVQALLTVLNNNEDCDIKQDCGQLVERLNVFKTAFSENEDDESLPAVALIRKLIAVLESIERLSLHLYDTPGSSYNLQILTRRLRFRLERAPGETSLIDRTGRMLKMEPLATVESLEQYLLKMVAKQWYDFDRSSFVFVRKLREGQSCVFRHQHDFDDNGIMYWIGTNAKTAYEWVNPAAYGLVVVTSSEGRNLPYGRLEDILSRDSSALNCHTNDDKSAWFAIDLGLWVVPSAYTLRHARGYGRSALRNWVFQVSKDGQNWTALYTHVDDSSLNEPGSTATWPLDPAREEKQGWRHVRIKQTGKNASGQTHYLSLSGFELYGTVTGVCEDQLGKAAKEAEANLRRQRRLVRSQVLKYMVPGARVIRGIDWKWRDQDGSAQGEGTVTGELHNGWIDVIWDAGGSNSYRMGAEGKFDLKLAPGYDPESAVSPKPVSSTVAGTPPSWSSLVKNNCPDKAPPSSSSSCVVVGSVAGSGSRKGSSSSVCSLASSSDVSLSCAKTERRAEEQVSDIHHDPIMLLSSNSAASGSSTCPPGGETVGEGDRKAGEAPAISMGMVSISSPDVSSVSDLSNKEVAVPRPLGSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRVANIARTNATNNMNLSRSSSDNNTNTLGRNAVSSATSPLMGAQSFPNLTTTGTTSTVTMSTSSVTSSNVATATTGLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRASTLLAELDDDEDLPEPDEEDDENEDDNQEEQEYEEVMEEEEYETKGGRRRTWDDDYVLKRQFSALVPAFDPRPGRTNVQQTTDLEIPAPGTPHSELLEEVECAPAPRLALTLKVTGLGSGREVELPLNFRSTIFYYVQRLLQLSCNGAIKTDKLRRIWEPTYTIMYREMKDSDKQKECGRLGCWSVEHVEQSLGTDTLPKNDLITYLQRNADPGFLRRWKLIGTNKSIRKNRNCSQLIAAYKDFCENGCKSLSMPAALATLQSADILNHSREQAQAKAGSSQNSCGVEDVLQLLRILFIVASDPYSARTPQEDGDDMLLFSVPPEEFTSKKITTKIVQQTEEPLALASGALPDWCEQLTSKCPFLIPFETRQLYFTCTAFGASRAIVWLQNRREATVERSRTASAVRRDDPGEFRVGRLKHERVKVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAELQKTELGIWLCDDDFPDDESRQVDLGGGLKPPGYYVQRSCGLFIAPYPQDSEELDRVTRLCHFLGVFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLLYASRGEESEHCTESQSEASTEDGHDALSVGSFEEDCKSEFILDPPKPKPPAWFQGILTWEDFELINPHRARFLRDIRELAVKRRQILGNRCLSEDEKNTQLQELMLKNPSGSGPPVSIEDLGLNFQFCPSSRVYGFSAVDLKPNGEDEMVTIDNVEEYVDLMFDFCMQTGVQKQMEAFRSGFNKVFPMEKLGSFSPEEVQMILCGNQSPSWSAEDIINYTEPKLGYTRESPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRDRLLAATMEKGFHLN",
        "proteome": null,
        "gene": "hectd1.L",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004842",
                "name": "ubiquitin-protein transferase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0046872",
                "name": "metal ion binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0016567",
                "name": "protein ubiquitination",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0061630",
                "name": "ubiquitin protein ligase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006511",
                "name": "ubiquitin-dependent protein catabolic process",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": false,
        "in_bfvd": false,
        "ida_accession": "f9064b4db62e9ec8b0f002a1696ec901a43abf6e",
        "counters": {
            "domain_architectures": 733,
            "entries": 39,
            "isoforms": 0,
            "proteomes": 0,
            "sets": 7,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 8,
                "ssf": 5,
                "profile": 4,
                "smart": 2,
                "pfam": 5,
                "cdd": 2,
                "panther": 1,
                "interpro": 12
            },
            "proteome": 0,
            "taxonomy": 1,
            "similar_proteins": 733
        }
    }
}