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{
"metadata": {
"accession": "A0A921UWW4",
"id": "A0A921UWW4_SORBI",
"source_organism": {
"taxId": "4558",
"scientificName": "Sorghum bicolor",
"fullName": "Sorghum bicolor (Sorghum)"
},
"name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial",
"description": [
"FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to coq6 from NADPH via a ferredoxin/ferredoxin reductase system"
],
"length": 515,
"sequence": "MLSRRRCFAAAVNRIRPLARAFCDAPDSGARRSQDHTEKVAGVKAPPDVLDVAIVGGGMVGLAVACALSNMPLTKHLRVAIIDSNPALKSRGYLDKNSIPDSRVSTVTPATMSFFKDIGAWEHVQQQRHAFFGKMQVWDYTGLGYTRYNARDVGKEYLGCVVENKVLCNSLLLRLQEELDDIENVIYPTRLVSLTFPLKSRQAGMKPTSSEPLSVGHTTEELHRSNLVKLDLSDGQSLYSKLVIGADGSKSNVRQIAGIKTTGWNYPQSAIICTVEHVVENDCAWQRFLPSGPIALLPIGNNFSNIVWTMSPEESLRHKSMSPEEFVKSVNHALDFGYGPHPRSTALDRYMEQFFSGIGNTAASTRECFEVPPKATGVVSERMAFPLSLMHSHDYVSKRLALVGDAAHTVHPLAGQGVNLGFGDAAALAKVIAEGVSVGSDVGDLTLLQRYEKDRKAANVAMTAVLDGFQKMYSVDFGPLNVVRAAAFHGAQYISPLKKNIISYAMGDTKWPLFR",
"proteome": null,
"gene": "COQ6",
"go_terms": [
{
"identifier": "GO:0071949",
"name": "FAD binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0106364",
"name": "4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006744",
"name": "ubiquinone biosynthetic process",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0016705",
"name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0050660",
"name": "flavin adenine dinucleotide binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "05cfc655a2faeb552505a63c917e19d98cb292e7",
"counters": {
"domain_architectures": 17050,
"entries": 15,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"pfam": 1,
"ssf": 1,
"hamap": 1,
"panther": 1,
"ncbifam": 2,
"prosite": 1,
"prints": 1,
"interpro": 6
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 17050
}
}
}