GET /api/protein/UniProt/A0A8M9Q308/?format=api
HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "A0A8M9Q308",
"id": "FLC2B_DANRE",
"source_organism": {
"taxId": "7955",
"scientificName": "Danio rerio",
"fullName": "Danio rerio (Zebrafish)"
},
"name": "Choline/ethanolamine transporter flvcr2b",
"description": [
"Choline uniporter that specifically mediates choline uptake at the blood-brain-barrier (PubMed:38302740). Responsible for the majority of choline uptake across the blood-brain-barrier from the circulation into the brain (By similarity). Choline, a nutrient critical for brain development, is a precursor of phosphatidylcholine, as well as betaine (By similarity). Also mediates transport of ethanolamine (By similarity). Choline and ethanolamine transport is not coupled with proton transport and is exclusively driven by the choline gradient across the plasma membrane (By similarity). Also acts as a heme b transporter (By similarity)"
],
"length": 485,
"sequence": "MDTRFNDINRVKMGDESKSVDGEVNDNTYYSKTDAEVNFEHRYTTPETRLYKKRWVIVCLFSSYSLCNSYQWIQYGIINNIFMRFYGVDSFTIDWMSMIYMLTYIPLIFPVSWLLDKKGLRVIALVAAALNCAGTWIKVASARPDLFPVTFLGQFTCSVAQVFILGMPSRIASVWFGSDEVSTACSIGVFGNQLGIAIGFLVPPILVPNVDDLDELAAHIRVMFYITAGVATFLFVLVVIVFQERPEIPPTLAQAAARRISPESYSYTASILRLLRNKAFILLVITYGLNVGCFYAVSTLLNRMIIEHYPGEEVNAGRIGLTIVVAGMVGSLICGIWLDRSKTYKQTTLAVYLMSLMGLVIYAFTLDLHHLWVVFITAGALGFFMTGYLPLGFEFAVELTYPESEGTSSGLLNCSAQVFGIIFTICQGKIMDSFGTLAGNLFLCAFLLIGTIITGCIKSDLRRQLANQQAQTADHLDTSPTQTRF",
"proteome": "UP000000437",
"gene": "flvcr2b",
"go_terms": [
{
"identifier": "GO:0022857",
"name": "transmembrane transporter activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0055085",
"name": "transmembrane transport",
"category": {
"code": "P",
"name": "biological_process"
}
}
],
"protein_evidence": 3,
"source_database": "reviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "04ed00d0ac42cc42b19f7796b389c797a27f88ba",
"counters": {
"domain_architectures": 1276664,
"entries": 10,
"isoforms": 2,
"proteomes": 1,
"sets": 2,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"cathgene3d": 1,
"cdd": 1,
"profile": 1,
"panther": 1,
"pfam": 1,
"interpro": 4
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 1276664
}
}
}