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{
    "metadata": {
        "accession": "A0A8M1G5D7",
        "id": "A0A8M1G5D7_URSMA",
        "source_organism": {
            "taxId": "29073",
            "scientificName": "Ursus maritimus",
            "fullName": "Ursus maritimus (Polar bear)"
        },
        "name": "DNA repair protein XRCC1",
        "description": [
            "Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity. Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity"
        ],
        "length": 620,
        "sequence": "MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGNSVGGAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRIFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPYGLSFIRFHSPPDKEEAEASPQKVTKLGQFRVKEEDEGASSLRPGALFFSRINKTPPAAASDPAGPSYAAATLQASSAASSASPVSRAVGGSSKPQESPKGKRKLDLNQEERKTPSKPSAQSSPPAIKRPKLPAPTRIPATTPVSAPARGTVPGKTREGTEPRGPRAGPQELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTPDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSRRYLMAGPGSSSEDEGSSHSGGSGDEAPKLPQKAAGPSSPQRPKMPEETKPASPGPQEDTDTDGEHSEEQGNGAEDSGDTEDELRRVAEQREQKQPPDQGENGEDPYAGSTDENTDNEGPPESPDLPVPELPDFFQGKHFFLYGEFPGDERRKLSRYVTAFNGELEDYMSDRVQFVITAQEWDPSFEEALMDNPSLVFVRPRWIYSCNEKQKLLPHQLYGVVPQA",
        "proteome": "UP000261680",
        "gene": "XRCC1",
        "go_terms": [
            {
                "identifier": "GO:0003684",
                "name": "damaged DNA binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0000012",
                "name": "single strand break repair",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0005634",
                "name": "nucleus",
                "category": {
                    "code": "C",
                    "name": "cellular_component"
                }
            },
            {
                "identifier": "GO:0006284",
                "name": "base-excision repair",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0006303",
                "name": "double-strand break repair via nonhomologous end joining",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 4,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "b5543bf2da4f3e0a20d46e3be85165c9568408a6",
        "counters": {
            "domain_architectures": 861,
            "entries": 17,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 3,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "pfam": 3,
                "ssf": 2,
                "cathgene3d": 2,
                "profile": 1,
                "smart": 1,
                "cdd": 2,
                "panther": 1,
                "interpro": 5
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 861
        }
    }
}