GET /api/protein/UniProt/A0A8J4BZB1/?format=api
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InterPro-Version: 108.0
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{
"metadata": {
"accession": "A0A8J4BZB1",
"id": "A0A8J4BZB1_9CHLO",
"source_organism": {
"taxId": "1737510",
"scientificName": "Volvox reticuliferus",
"fullName": "Volvox reticuliferus"
},
"name": "Cysteine protease",
"description": [
"Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. In addition to the protease activity, also mediates delipidation of PE-conjugated ATG8 proteins"
],
"length": 527,
"sequence": "MNVSVRLPARNRSCPTLAVRLDSPTCSIVPGRWVGPWMLCKSLEALFSPLVCERPMGLHLHVACGSGGGAPELDTTAIRAQMAAAAASTTAQSTSKREEGVPIHGRCKVDTAPAWDGDSAPTLCSGSAQRGGDTDTDSGGRREGGSLQAAVRSQGWDDPDQRGSDGSLQAAGAAGTDTAADRDSQSRPPLRGEELLGCVTDLQRTGKRCQGASARATFETKRGPVEDGAICDGPDVQPARRPGPACGTASSSPGTLAATAAEAASAVAVAGVEATTVNGDHRAEALGFGAVGCREVSSPGAIAQLHGADWAGDAAGGRPSGHCRDGNAAGPSGRPAASTPVLLLVPLTLGMDKINTVYLPQLQQILSWPQSVGIVGGRPSASLYLCGVQGSSFLYLDPHEAQPAVRWGIGGADASRTHDAVTGSGPAVALPHSSLVTYFCDTVRMLPAAALDPSMAIGFLCMGPADLEDLFSRLDALAKEYSLAPLMTLTSGGAQAGAGLEDDFEEPEFGAGQPAGQQQQLEEWELV",
"proteome": "UP000747110",
"gene": "Vretimale_3367",
"go_terms": [
{
"identifier": "GO:0008234",
"name": "cysteine-type peptidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0019786",
"name": "protein-phosphatidylethanolamide deconjugating activity",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "6d3a3c7a42f0bbe649d79e43e20fc010e35776db",
"counters": {
"domain_architectures": 8470,
"entries": 6,
"isoforms": 0,
"proteomes": 1,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"ssf": 1,
"pfam": 1,
"panther": 1,
"interpro": 3
},
"proteome": 1,
"taxonomy": 1,
"similar_proteins": 8470
}
}
}