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{
    "metadata": {
        "accession": "A0A8I5YPY6",
        "id": "A0A8I5YPY6_PONAB",
        "source_organism": {
            "taxId": "9601",
            "scientificName": "Pongo abelii",
            "fullName": "Pongo abelii (Sumatran orangutan)"
        },
        "name": "Receptor-type tyrosine-protein phosphatase C",
        "description": [
            "Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation threshold to limit autoreactivity"
        ],
        "length": 1144,
        "sequence": "MTMYLWLKLLAFGFAFLDTEVFVTGQSPAPSPTDTYLSASETTTLSPSGSAVISTTTIATTPSKPTCGEKYANIPVDYLYNKETKLFMAKLNVNETVECEKNNCINNELHNLKECENSLSIFHNSCTAPYRKLKLVVPPDVEKFQLLDCTQDEKANTTICLKWKNIKNFTCDPRNITYRFQCGNTTFNKKEIKLENLEPEHEYKCDSEILYNNHKYTNTSKIIKTDFGTPGKPQNIVCKSEAAHQGVITWNPPQRSFNNFTLCYVNKTEKKCLILDKNLTEYDLQNLKPYTKYDLSLHAYIIAKVQRNGTAATCNFTTKSAPASQVQKMTISMTSDNSMHVKCGPPRDRNGPNERYYLEVEAGNTLVRNESHKNCDFRVKDLQYLTNYTFKAYFHNGKYPGEPLILHKSTSYNSKALIAFLTFLIIVTSIALLVVLYKIYDLHKKRSCNLDEQQELVERDDEKQLMNVEPIHADILLETYKRKIADEGRLFLAEFQSIPRVFSKFPIKEARKPFNQNKNRYVDILPYDYNRVELSEINGDAGSNYINASYIDGFKEPRKYIAAQGPRDETIDDFWRMIWEQKATVIVMVTRCEEGNRNKCAEYWPSMEEGTRAFGDVVVKINQHKRCPDYIIQKLNIVNKKEKATGREVTHIQFTSWPDHGVPEDPHLLLKLRRRVNAFSNFFSGPIVVHCSAGVGRTGTYIGIDAMLEGLEAENKVDVYGYVVKLRRQRCLMVQVEAQYILIHQALVEYNQFGETEVNLSELHPYLHNMKKRDPPSEPSPLEAEFQRLPSYRSWRTQHIGNQEENKNKNRNSNVIPYDYNRVPLKHELEMSKESEHDSDESSDDDSDSEEPSKYINASFIMSYWKPEVMIAAQGPLKETIGDFWQMIFQRKVKVVVMLTELKHRDQEICAQYWGEGKQTYGDIEVDLKGTDKSSTYTLRVFELRHSKRKDSRTVYQYQYTNWSVEQLPEEPKELISLIQVLKQKLPQKNSSEGNKHHKSTPLLIHCRDGSQQTGIFCALLNLLESAETEEVVDIFQVVKALRKARPGMVSTFEQYQFLYDIIASTYPAQNGQVKKNNHQEDKIEFDNEVDKVKQDANCVNPLGAPEKLPEAKEQAEGSEPMSGTEGPEHSVNGPASPALNQGS",
        "proteome": "UP000001595",
        "gene": "PTPRC",
        "go_terms": [
            {
                "identifier": "GO:0005515",
                "name": "protein binding",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0004725",
                "name": "protein tyrosine phosphatase activity",
                "category": {
                    "code": "F",
                    "name": "molecular_function"
                }
            },
            {
                "identifier": "GO:0006470",
                "name": "protein dephosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0016311",
                "name": "dephosphorylation",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            },
            {
                "identifier": "GO:0050852",
                "name": "T cell receptor signaling pathway",
                "category": {
                    "code": "P",
                    "name": "biological_process"
                }
            }
        ],
        "protein_evidence": 3,
        "source_database": "unreviewed",
        "is_fragment": false,
        "in_alphafold": true,
        "in_bfvd": false,
        "ida_accession": "8c053afb61557dfb5c0b749f6a1cea7ce5c221cc",
        "counters": {
            "domain_architectures": 255,
            "entries": 32,
            "isoforms": 0,
            "proteomes": 1,
            "sets": 4,
            "structures": 0,
            "taxa": 1,
            "dbEntries": {
                "cathgene3d": 2,
                "ssf": 2,
                "cdd": 3,
                "smart": 3,
                "pfam": 4,
                "profile": 3,
                "pirsf": 1,
                "panther": 1,
                "prints": 1,
                "prosite": 1,
                "interpro": 11
            },
            "proteome": 1,
            "taxonomy": 1,
            "similar_proteins": 255
        }
    }
}