HTTP 200 OK
Allow: GET, HEAD
Content-Type: application/json
InterPro-Version: 108.0
InterPro-Version-Minor: 0
Vary: Accept
{
"metadata": {
"accession": "A0A8H3SNB8",
"id": "A0A8H3SNB8_ASPTU",
"source_organism": {
"taxId": "5068",
"scientificName": "Aspergillus tubingensis",
"fullName": "Aspergillus tubingensis"
},
"name": "Histone H3",
"description": [
"Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling",
"Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division"
],
"length": 185,
"sequence": "MPPKTGGRGRGRKSVTAAPRQSTAGDRAAASSSTAATTASPAAKKVRKSTGATRGGKRPAGKAPRESDVQPGDPTPQGRVRRYKPGTVALKEIRKYQRSYDLLIQKLPFARLVREVALDLLPSEVGAELRWQSHAIQALQEAAEAFLVHLFEDTNLCAIHAKRVTIMQKDIQLARRIRGVWGGLG",
"proteome": null,
"gene": "AtubIFM56815_010969",
"go_terms": [
{
"identifier": "GO:0046982",
"name": "protein heterodimerization activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003677",
"name": "DNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0030527",
"name": "structural constituent of chromatin",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0000786",
"name": "nucleosome",
"category": {
"code": "C",
"name": "cellular_component"
}
}
],
"protein_evidence": 3,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": true,
"in_bfvd": false,
"ida_accession": "e204a9d55ad7bafe2e507ca80f663a0ac2378352",
"counters": {
"domain_architectures": 87265,
"entries": 11,
"isoforms": 0,
"proteomes": 0,
"sets": 1,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 1,
"ssf": 1,
"smart": 1,
"cdd": 1,
"pfam": 1,
"panther": 1,
"prosite": 1,
"prints": 1,
"interpro": 3
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 87265
}
}
}