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{
"metadata": {
"accession": "A0A8F5PHH2",
"id": "A0A8F5PHH2_9CALI",
"source_organism": {
"taxId": "2809180",
"scientificName": "Bavovirus sp.",
"fullName": "Bavovirus sp."
},
"name": "Genome polyprotein",
"description": [
"Displays NTPase activity, but no helicase activity. Induces the formation of convoluted membranes derived from the host ER. These remodeled membranes probably form the viral factories that contain the replication complex. Together with NS2 and NS4, initiates the formation of the replication complex",
"Probable key protein responsible for the formation of membrane alterations by the virus. Induces the formation of convoluted membranes derived from the host ER. These remodeled membranes probably form the viral factories that contain the replication complex. Together with NS2 and NTPase, initiates the formation of the replication complex",
"Together with NTPase and NS4, initiates the formation of the replication complex. Induces the proliferation of the host smooth ER membranes forming long tubular structures. These remodeled membranes probably form the viral factories that contain the replication complex",
"Viral genome-linked protein is covalently linked to the 5'-end of the positive-strand, negative-strand genomic RNAs and subgenomic RNA. Acts as a genome-linked replication primer. May recruit ribosome to viral RNA thereby promoting viral proteins translation. Interacts with host translation initiation complex to allow the translation of viral proteins"
],
"length": 2327,
"sequence": "MVGEMLTFAGLIGWEDDDGDLSFGSNHTYWGLFGDPATVRKKVDGLFHDIRTGGSCPQATTSPTPEPNPTPEQVIPNPPEPSFWRRLIDGVTPPQEPPLLSAITSLISLLGGLANLTFTALVEKVKPVALLTILRAHGWRLTIPCLTAVLELYGMVRSTTDLLVDGIGWFIDFISRHLPCKLQAGGGEDSDTDLEELYTAENPSRLSPRVLQLIGAVVSLPVALLLGRAACRPILRFLGSLSRVNTVATFIKNVASLVSWGKNQLASQRIRRTIGGLIMVEEEVARHINNSTAPQLEAYSNTIDQLLEEARERQVSHPGHPLLSALTKHASDLKELQNQLRGKLSLLAKRDPPAFYLFTGPPGIGKTTLVQHLAARLSPIAPSNFPGHLDHYDTYNPGPVCIWDEMTNTPPDLMVQHVLGMVNSTPYPLNCDRPENKGMVFNSRVVFATSNLSTPLDPGHPLAGAFYRRVQIIDCSAPAISNYITETGEMPPSTHYRQDGSHITLKKRPRMAYTPQGDLLTSDGVARKGRVTPTTPDAILTSLRGTVVMEAGRRILLVVDKNWPEALPTSWMFESRGHQVDVIVDGPETNQEANVLILAVMNANDWPAHRVAGLLKKVNPALWSLAYVAGTPEVVVASKRISPCDLMDHVKRTWTAPQNFREEQGWHPDWPAYYAKCREAGRLPGYILLGIDPALAPDLATHLHQWASRRGIPLPIYDGTKNPCAAIERAETEILTAIVMVKPTDDPDLKVTHFDPTRPPGLSLSDVIQTENNEALEKFLGHVWAPGTISPHILHRITPACELDVSDSSTGVGAVMNHFSLASGVRVIWQAWKNAGSTAQFFQTLLTMAARPEPRLTVLHWGDSTYWLYTSTCVGFAITPRIAPHRLPGCARPRPAGDRSLYGLLSEMLSTFLTALRNAAPLILTLYSWNQLNSTEMEKKKGKTKHGRGRRHAGGGRGPRLTDEDYDEWQQMREDWREDVTAEQYYQAKYGENRDTKTSQRYDAWRRLKDLRAGQNDPRMSRPETRREAGLVSRHHGLSRQDLGFATSRAERRLATYDASNPGDDEAPRRLRHHMEGGITSPVVPALSGSLEVGWAVHLGSGRFILPKHLGATTIAGHPFVVCGLRNVDLLFVDCQALRSIPQVRIGTGHPVKLHGRGYINASKTTATHLLPVGTVQGYSYNLLAGITKQGDCGLPLYDAAGGVVGIHVARNQVGSICLAYQQLTEAAARPLRSFRGLDVVDSEVPSGPPMTVTRYWVAPGMEFDEQMPYQPGLVGSNDPRNPAPLVTILTSGLAPYTDPGPDIPPAELALARAQVTAALQALIGVEVSPNLDFAAAWGSLNKDTSCGPLVPGKKRDYMDEAGNLLPGTLRDHLSTSWGIATTGKALRHIYALALKDELLPRRKIYETPKKRLLWGCDAGVALAAAGVFQPVYERIKATAAWGPISVGICLERPEVFNAFQHRFTGPVSCLDYSGWDSTMHHAVITAAVEILSVFAEDTPLTHSVVSTLTSPAIGCFMGCEVTVKRGLPSGQPGTSMINSVCHMLYFCMALNISARGACLPPLQNPILDCELATYGDDCIYKFPTLYQGAFGNFIQALRTLGLKPTAPDKTSDIALGLRIVYLKRELRDAEGNWRDGPVLDLDSIVRQAYWVRGTAHRDPREVATRVHDGRGLQLDLALAALSQHGPEVFSQNVHPFIRTALASGCPISLTTWEVAHQWWKDFSASLSTAEGDITTLVMSPKVDYVMEGVTTPPAPRGQAPTGTPQTTQELSLATSGMVVTAPDTGVPVAPQPVAPQAPTIIEASGGITTLPPDMASMFVQIGRLGWNGTNPTGTMLGTFDLGPALNPFTRLISQAYCAWGGGFEFQVMLSGSGAYGGRLLIGIFPPGINPGNQDPTAFPHFYVDARESSPVTFPVPDLNPARYHSTTAADLTTSVAIFVAAPLLNPFSANNGYSCEITVLARPGPDFGFAMLRTPTTTEVTVIRDALGRSTAGWLGCRWATHITSITPFLGARDTRVYNHFTSQGTTAGWGNGWPYTRIYVNIYNTSTNRPGTPGTGVTAGQFLAVQAAPDSGQAPTVIPGIPPGWTDLPTSQVTVNQGADPTAGSGAMYVGVFATHVNGSGPDIAEAFSERFFQQNGMIASGTTSATIISVPNNVSNQTLAFAIGETRTGAPASNAQTIVASCMCWFTASNTSPGDNALTVPGYNGRAAPYHHTILSFNSHVPTNYPGGGTIGSSQPVPLSSTLAANPSDGWDSTRMAVWNLSGGGYTWQMGMLSDGTMVTGNFTGTVSLTTPHEISFQGFSSITAPLQPPTPNGNDAAFRLVNW",
"proteome": null,
"gene": null,
"go_terms": [
{
"identifier": "GO:0003723",
"name": "RNA binding",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0003724",
"name": "RNA helicase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0004197",
"name": "cysteine-type endopeptidase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0006508",
"name": "proteolysis",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0003968",
"name": "RNA-directed RNA polymerase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0039694",
"name": "viral RNA genome replication",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0006351",
"name": "DNA-templated transcription",
"category": {
"code": "P",
"name": "biological_process"
}
},
{
"identifier": "GO:0004386",
"name": "helicase activity",
"category": {
"code": "F",
"name": "molecular_function"
}
},
{
"identifier": "GO:0005524",
"name": "ATP binding",
"category": {
"code": "F",
"name": "molecular_function"
}
}
],
"protein_evidence": 4,
"source_database": "unreviewed",
"is_fragment": false,
"in_alphafold": false,
"in_bfvd": false,
"ida_accession": "f89567de6acdce05a71dbdd7260a34874e0ff275",
"counters": {
"domain_architectures": 13,
"entries": 37,
"isoforms": 0,
"proteomes": 0,
"sets": 6,
"structures": 0,
"taxa": 1,
"dbEntries": {
"cathgene3d": 7,
"profile": 3,
"ssf": 4,
"cdd": 2,
"pfam": 5,
"prints": 2,
"interpro": 14
},
"proteome": 0,
"taxonomy": 1,
"similar_proteins": 13
}
}
}
